New drug combo may reduce chronic transplant complications in blood cancer patients
NCT ID NCT03680092
First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 31 times
Summary
This study tested whether a combination of two drugs, cyclophosphamide and abatacept, could lower the risk of chronic graft-versus-host disease (GVHD) after a stem cell transplant in people with high-risk blood cancers. GVHD happens when donor cells attack the patient's body. The trial enrolled 43 participants and compared the new drug combo to standard care. The main goal was to see if fewer patients developed moderate or severe chronic GVHD one year after transplant.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
Conditions
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As listed by the trial registrant
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