GVHD
Clinical trials for GVHD explained in plain language.
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New hope for kids: drug may prevent transplant complications
Disease control Recruiting nowThis study tests whether adding the drug vorinostat to standard care can prevent graft-versus-host disease (GVHD) in children and young adults (ages 1-26) with non-cancerous blood disorders who are getting a bone marrow transplant. GVHD is a serious complication where donor cells…
Matched conditions: GVHD
Phase 2 • Sponsor: Sung Won Choi • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Can patients stop Anti-Rejection drugs sooner after transplant?
Disease control Recruiting nowThis study tests whether patients can safely stop the drug tacrolimus earlier than usual after a stem cell transplant. Tacrolimus is given to prevent graft-versus-host disease (GVHD), but newer methods have lowered GVHD risk. The trial will enroll 50 people with blood cancers and…
Matched conditions: GVHD
Phase 1 • Sponsor: Stanford University • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Which drug better prevents transplant complications in older leukemia patients?
Disease control Recruiting nowThis phase 3 trial tests two drugs, Thymoglobulin and Grafalon, to see which one better prevents graft-versus-host disease (GVHD) in patients aged 50-70 with acute myeloid leukemia or myelodysplastic syndrome. All participants receive a stem cell transplant from a matched unrelat…
Matched conditions: GVHD
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Light therapy tested for painful mouth sores after stem cell transplant
Symptom relief Recruiting nowThis phase 2 trial tests whether photobiomodulation (PBM) — a type of light therapy — can safely treat oral chronic graft-versus-host disease (GVHD), a painful mouth condition that can occur after a stem cell transplant. About 44 participants who have not responded to at least on…
Matched conditions: GVHD
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New study tests sleep coaching for transplant recovery
Symptom relief Recruiting nowThis study looks at whether a sleep education program can improve sleep and daily activity for adults getting a bone marrow transplant. Sixty participants will wear a device to track their sleep and movement. The goal is to see if better sleep helps them feel better during recove…
Matched conditions: GVHD
Sponsor: Scripps Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Simple blood test could predict transplant complications
Knowledge-focused Recruiting nowThis study looks at a new method to measure special immune cells called iNKT cells in the blood of patients who have had a stem cell transplant. These cells may help predict serious complications like graft-versus-host disease (GvHD) and relapse. Researchers will test 75 adults w…
Matched conditions: GVHD
Sponsor: University Hospital Pilsen • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Depression may worsen GvHD symptoms, new study investigates
Knowledge-focused Recruiting nowThis study looks at how depression and other mental health issues impact symptom severity and quality of life in people with graft-versus-host disease (GvHD). Researchers will follow 200 adults with GvHD, using questionnaires to measure psychiatric status and symptoms. The goal i…
Matched conditions: GVHD
Sponsor: Medical University of Gdansk • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC