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New combo therapy aims to tame stem cell transplant complications

NCT ID NCT05120570

First seen Jan 06, 2026 · Last updated Jun 20, 2026 · Updated 25 times

Summary

This study tested a new drug called VIC-1911 added to standard medications to prevent graft-versus-host disease (GVHD) in 16 adults with blood cancers receiving a stem cell transplant. The goal was to find a safe and effective dose that reduces GVHD and relapse. Results are still being analyzed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Masonic Cancer Center at University of Minnesota

    Minneapolis, Minnesota, 55455, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VIC-1911

What this could lead to

If successful, this could lead to a safer stem cell transplant with less risk of graft-versus-host disease and relapse.

What could go wrong

This is an early-phase trial with only 16 participants, so results may not apply broadly. The drug may cause side effects or not work as hoped.

Conditions

The condition(s) this trial relates to.

lymphoma Myelodysplastic Syndromes Myeloproliferative Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.