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New hope for rare blood cancers: fedratinib shows promise in early trial

NCT ID NCT05177211

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times

Summary

This study tested a drug called fedratinib in 25 adults with rare blood cancers (MDS/MPN and CNL). The goal was to see if the drug could shrink the spleen and improve blood counts. While not a cure, the treatment aims to control the disease and reduce symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

Conditions

The condition(s) this trial relates to.

atypical chronic myeloid leukemia, BCR-ABL1 negative chronic neutrophilic leukemia myelodysplastic syndrome myelodysplastic/myeloproliferative neoplasm Myeloproliferative Disorders myeloproliferative neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.