MUSCLE WEAKNESS

This is an early-stage safety study testing a new type of treatment called anito-cel for adults with generalized myasthenia gravis, a chronic autoimmune disease that causes severe muscle weakness. The therapy involves collecting a patient's own immune cells, genetically modifying…

This study is testing whether taking creatine supplements along with exercise helps breast cancer survivors recover strength and endurance more quickly after chemotherapy. Researchers will compare 60 breast cancer survivors doing exercise with or without creatine to healthy women…

This study is testing whether an 8-week Pilates exercise program can improve breathing and overall health in overweight and obese women. Participants will do core and abdominal exercises three times a week. Researchers will measure lung function, core strength, and quality of lif…

This study aims to understand if a special flywheel exercise machine can help prevent muscle and strength loss caused by not using a limb, similar to what astronauts experience in space. Researchers will have 16 healthy, active volunteers wear a special shoe and use crutches for …

This study aims to understand why survivors of childhood acute lymphoblastic leukemia (ALL) often experience muscle weakness. Researchers will compare 60 survivors with healthy volunteers using MRI scans, blood tests, and muscle biopsies to examine how cancer treatment affects mu…

This study is exploring new ways to control robotic leg braces (exoskeletons) to help children and young adults with conditions like cerebral palsy or muscular dystrophy walk better in different daily situations. Researchers are testing how different control settings work during …

This study aims to understand why many people who survive a serious illness in the Intensive Care Unit (ICU) struggle to regain their muscle strength and physical abilities. Researchers will follow about 200 adult ICU survivors for a year, measuring their muscle function and look…

This small pilot study aims to understand why some patients develop severe muscle weakness after a long stay in intensive care. Researchers will collect blood and small muscle samples from up to 20 surgical patients at high risk for this condition. By analyzing these samples, the…

This study aims to identify factors that influence how well leg muscle strength recovers after a common back surgery called a lumbar microdiscectomy. Researchers will observe 40 patients with leg weakness from a herniated disc to see if factors like the severity and duration of w…