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Space muscle saver? flywheel workout tested for astronauts

NCT ID NCT06631053

Knowledge-focused Sponsor: Lance Bollinger Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a type of exercise using a flywheel machine can help prevent muscle loss and weakness during space travel. Sixteen healthy adults who exercise regularly will take part. They will use crutches and a special shoe to mimic the reduced weight-bearing of space, and some will do the flywheel workouts to see if it protects their muscles.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
velocity-based flywheel inertial training (FIT) exercise
What this could lead to
If successful, this could lead to better exercise programs for astronauts to prevent muscle and strength loss during long space missions.
What could go wrong
This is a small, early-stage study in healthy adults on Earth, not in space. Results may not translate to real spaceflight conditions or to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 16 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Regularly engaging in aerobic exercise (\> 150min/wk) and resistance exercise (\>1 time per week) for the past 12 months * Education greater than or equal to bachelor's degree (any field) Exclusion Criteria: * Waist circumference \< 55cm or \> 90cm (F) and \< 75cm or \> 100cm (M) * Body mass index \< 18.5 or \> 29.9 * Shoe size \< 25 or \>29cm. * Not regularly engaging in exercise for previous 12 months * Tobacco use within previous 6 months * Blood clotting disorder * Heart arrhythmia * Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant * Diagnosed cardiovascular, pulmonary, renal, or metabolic disease * Pregnancy (within previous 6 months) * Oral contraceptive use (within previous three months) * High resting blood pressure (\>140 systolic and/or \> 90 diastolic) * Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery) * Low back or leg injury in previous 6 months * Currently taking medication to assist with sleep * Muscle, bone, or joint injury that limits physical activity within previous 6 months * Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)

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Conditions

The condition(s) this trial relates to.

Motor Activity Muscle Weakness muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle atrophy Muscle weakness

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40506, United States

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