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Wrist in a cast? Opposite-Arm workouts might save your strength

NCT ID NCT07166198

Knowledge-focused Sponsor: Kansas State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how muscle weakness develops when a wrist is immobilized for 7 days in women aged 40-65. It also tests whether strength training the opposite arm can help maintain muscle and nerve function in the casted arm. Twenty women will wear a wrist cast and either do opposite-arm exercises or not, with measurements of strength, muscle size, and brain activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward simple exercise strategies to prevent muscle loss during periods of immobilization, like after an injury.
What could go wrong
This is a small, early-stage study with only 20 participants. It is designed to understand the problem, not to test a treatment, so results may not lead to immediate solutions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women between 40-65 years of age * Baseline handgrip strength \>16Kg Exclusion Criteria: * Personal or family history of blood clots * Current use of anticoagulant medications * Neuromuscular or metabolic diseases (e.g., multiple sclerosis, diabetes) * Arthritis * Osteoporosis or osteopenia * History of myocardial infarction within the past year * Chronic pain ≥3/10 for ≥3 months * Uncontrolled hypertension (≥140/90 mmHg) * Upper extremity surgery within the past year * Use of assistive hand or arm device within the past year * Fall involving the upper extremities within the past year * Upper extremity injuries preventing safe participation * Current use of muscle relaxants, benzodiazepines, or similar drugs * Smoking within the past 6 months * History of drug or alcohol abuse within the past year * Severe anxiety or claustrophobia * Pregnancy (current or planned) * Allergies to medical adhesives * High risk of sarcopenia (per SARC-F) * Contraindications to TMS or MRI * Upper-body resistance training within the past 6 months * Inability/unwillingness to refrain from resistance training during study

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Conditions

The condition(s) this trial relates to.

Muscle Weakness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscle weakness

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Neuromuscular Physiology Laboratory

    RECRUITING

    Manhattan, Kansas, 66506, United States

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