Methamphetamine use disorder

This study tests a non-invasive brain stimulation technique called targeted temporal interference stimulation (tTIS) aimed at the caudate nucleus. The goal is to reduce drug cravings and improve decision-making in 60 adults with methamphetamine use disorder. Participants will rec…

This study tests whether an app that gives financial rewards for drug-negative saliva tests works for older adults with opioid, cocaine, or methamphetamine use disorder. Researchers will compare results between older and younger participants to see if age affects how well the app…

This pilot study tests whether combining ketamine injections with talk therapy is a safe and acceptable way to treat moderate-to-severe methamphetamine use disorder in 17 publicly insured patients, some of whom have or are at risk for HIV. Participants receive three monitored ket…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce methamphetamine use in people already receiving methadone maintenance therapy. Fifty-five adults with both opioid and methamphetamine use dis…

This study tested a program that provides dedicated care navigation to people with methamphetamine use disorder. The goal was to help them enter and stay in addiction treatment, and to prevent overdoses. 192 adults from the Denver Health system who had a methamphetamine-related v…

This study tested whether taking naltrexone pills only when needed, combined with a smartphone app that offers real-time support, can help men who have sex with men reduce methamphetamine use. Sixty participants were randomly assigned to receive either the drug or a placebo, plus…

This early-phase study tested whether a hormone called progesterone could help new mothers avoid returning to methamphetamine use after childbirth. 34 postpartum women with a history of meth use but currently abstinent took either progesterone or a placebo for 12 weeks. The goal …

Researchers at Hanoi Medical University are studying whether methadone clinics can effectively screen, treat, and keep people with methamphetamine use disorder in care. The trial enrolls 60 adults who test positive for meth but not opioids. Participants receive counseling and inc…

This study tested whether a non-invasive brain stimulation technique called theta burst stimulation (TBS) could help reduce cravings and improve symptoms in people with methamphetamine use disorder. Twenty-two adults in Indonesia who had not yet received treatment were given TBS …

This study tested a brain stimulation technique called closed-loop tACS in 21 people with methamphetamine addiction. The device uses brain wave patterns to deliver targeted electrical stimulation aimed at reducing cravings. Researchers measured craving levels and impulse control …

This study measures two blood proteins, LRFN5 and OLFM4, in people with methamphetamine use disorder, those with methamphetamine-induced psychosis, and healthy volunteers. Researchers want to see if these markers are linked to inflammation and symptom severity. The study involves…

This study tests whether recalling a positive memory can improve mood and decision-making in 80 adults recovering from methamphetamine use disorder. Participants will do computer tasks and brain scans before and after remembering a happy event or a neutral memory. The goal is to …

This study measured a specific enzyme in the blood of 93 people to see if it is linked to psychotic symptoms in methamphetamine users. Participants included people with methamphetamine use disorder, those with methamphetamine-induced psychosis, and healthy volunteers. The goal wa…