METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Clinical trials for METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA explained in plain language.
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New hope for tough pancreatic cancer: combo therapy tested
Disease control OngoingThis study tests a combination of two drugs, BXCL701 and pembrolizumab, in people with metastatic pancreatic cancer that has spread. The goal is to see if this treatment can stop the cancer from growing for at least 18 weeks. About 22 participants will receive the drugs and be cl…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Georgetown University • Aim: Disease control
Last updated May 26, 2026 09:08 UTC
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Sound waves could supercharge chemo against tough pancreatic cancer
Disease control OngoingThis study tests a new method called sonoporation, which uses ultrasound and tiny gas bubbles to help chemotherapy drugs get into cancer cells more effectively. About 120 adults with advanced pancreatic cancer will receive either standard chemotherapy alone or chemotherapy plus s…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Flemming Forsberg • Aim: Disease control
Last updated May 26, 2026 09:07 UTC
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Antibiotic boosts chemo in pancreatic cancer fight?
Disease control OngoingThis early-phase study tested whether adding the antibiotic ciprofloxacin to standard chemotherapy could help control metastatic pancreatic cancer. Ten adults with untreated, advanced pancreatic cancer took part. The goal was to see if the combination improved tumor response, but…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National University Hospital, Singapore • Aim: Disease control
Last updated May 26, 2026 09:05 UTC
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New hope for pancreatic cancer: experimental drug combo tested in large trial
Disease control OngoingThis phase 3 trial tests whether adding the experimental drug quemliclustat to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 610 participants who have not had prior treatment for advanced disease will receive either the drug combo or a pl…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Arcus Biosciences, Inc. • Aim: Disease control
Last updated May 26, 2026 09:04 UTC
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Can a common diabetes pill help pancreatic cancer patients manage blood sugar?
Disease control OngoingThis study looks at how safe and effective glipizide, a standard diabetes drug, is for lowering blood sugar in people with pancreatic cancer. About 29 adults with active pancreatic cancer and high blood sugar will take glipizide and have their glucose levels monitored. The goal i…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:01 UTC
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New hope for advanced pancreatic cancer: drug combo shows promise in early trial
Disease control OngoingThis study tests two experimental drugs (AK112 and cadonilimab) plus standard chemotherapy in people with stage IV pancreatic cancer that has spread. The goal is to see if the combination is safe and can shrink tumors or slow the cancer. About 110 adults who have not had prior tr…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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New hope for pancreatic cancer: drug combo shows promise in early trial
Disease control OngoingThis study tests a new drug called mitazalimab combined with standard chemotherapy in people with metastatic pancreatic cancer that has spread. The goal is to see if the combination is safe and can shrink tumors. About 94 adults who have not had prior chemotherapy for this cancer…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Alligator Bioscience AB • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New hope for pancreatic cancer: immune-boosting drug added to chemo
Disease control OngoingThis study tests whether adding botensilimab, an immune-boosting drug, to standard chemotherapy helps people with metastatic pancreatic cancer live longer without their cancer growing. It includes 81 adults whose cancer got worse after initial treatment. Participants are randomly…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Agenus Inc. • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New combo targets Hard-to-Treat pancreatic cancer
Disease control TerminatedThis early-stage trial tests a new drug called CA-4948 added to standard chemotherapy for people with pancreatic cancer that has spread or can't be removed. The goal is to find the safest dose and see if the combination can shrink tumors or stop them from growing. About 43 adults…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Personalized cell therapy trial for advanced cancers withdrawn before enrollment
Disease control TerminatedThis early-stage trial aimed to test the safety and effectiveness of STIL101, a personalized cell therapy made from a patient's own tumor-fighting T cells, for several advanced cancers including pancreatic, colorectal, kidney, cervical, and melanoma. The treatment involved collec…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New drug combo shows promise for tough pancreatic cancer
Disease control OngoingThis study tests whether combining two drugs, pembrolizumab (which helps the immune system fight cancer) and olaparib (which stops cancer cells from repairing themselves), can help people with metastatic pancreatic cancer that has a specific genetic feature or has responded well …
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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New imaging method aims to spot hidden cancers, but study never started
Diagnosis TerminatedThis study was designed to test a new type of PET scan that uses two special substances to find cancer cells with a marker called CA19-9. It was planned for people with pancreatic, bladder, or gastrointestinal cancers. However, the study was withdrawn before any participants were…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 26, 2026 08:58 UTC
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Enzyme pills aim to fight weight loss in advanced pancreatic cancer
Symptom relief OngoingThis study tests whether taking pancreatic enzyme pills (pancrelipase) can help people with metastatic pancreatic cancer maintain or gain weight. The study includes 17 participants who are starting chemotherapy. Researchers will compare two different dosing schedules and measure …
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 09:04 UTC