New hope for pancreatic cancer: experimental drug combo tested in large trial

NCT ID NCT06608927

Ongoing Disease control Sponsor: Arcus Biosciences, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 30 times

Summary

This phase 3 trial tests whether adding the experimental drug quemliclustat to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 610 participants who have not had prior treatment for advanced disease will receive either the drug combo or a placebo plus chemo. The main goal is to compare overall survival between the two groups.

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Contacts and locations

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Locations

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Phoenix, Arizona, 85054, United States
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Tucson, Arizona, 85724, United States
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La Jolla, California, 92093, United States
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Los Alamitos, California, 90720, United States
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Los Angeles, California, 90033-5315, United States
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Roseville, California, 95661, United States
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San Francisco, California, 94158, United States
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Santa Monica, California, 90404, United States
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Denver, Colorado, 80218, United States
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New Haven, Connecticut, 06520, United States
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Jacksonville, Florida, 32224-1865, United States
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Miami, Florida, 33176, United States
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Atlanta, Georgia, 30318, United States
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Atlanta, Georgia, 30322, United States
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Arlington Heights, Illinois, 60005, United States
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Chicago, Illinois, 60611, United States
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Indianapolis, Indiana, 46202, United States
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Wichita, Kansas, 67208, United States
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Baton Rouge, Louisiana, 70809, United States
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Ann Arbor, Michigan, 48109, United States
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Grand Rapids, Michigan, 49503, United States
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Minneapolis, Minnesota, 55404, United States
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Rochester, Minnesota, 55905, United States
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Hattiesburg, Mississippi, 39401, United States
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Kansas City, Missouri, 64111, United States
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Omaha, Nebraska, 68105, United States
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New Brunswick, New Jersey, 08903-2681, United States
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Buffalo, New York, 14263, United States
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New York, New York, 10016, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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New York, New York, 10128, United States
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Rochester, New York, 14642, United States
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Cleveland, Ohio, 44106, United States
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Oklahoma City, Oklahoma, 73104, United States
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Philadelphia, Pennsylvania, 19111-2497, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Nashville, Tennessee, 37232, United States
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Austin, Texas, 78705, United States
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Dallas, Texas, 75246, United States
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Dallas, Texas, 75390, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78240, United States
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Webster, Texas, 77598, United States
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Fairfax, Virginia, 22031, United States
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Spokane, Washington, 99208, United States
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Vancouver, Washington, 98684, United States
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Madison, Wisconsin, 53792, United States
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Camperdown, Australia
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Murdoch, Australia
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Wollongong, Australia
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Salzburg, Austria
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Sankt Pölten, Austria
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Vienna, Austria
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Anderlecht, Belgium
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Bonheiden, Belgium
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Kortrijk, Belgium
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Ottawa, Canada
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Sherbrooke, Canada
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Toronto, Canada
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Brno, Czechia
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Nový Jičín, Czechia
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Prague, Czechia
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Dijon, France
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Lyon, France
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Poitiers, France
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Villejuif, France
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Bochum, Germany
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Frankfurt am Main, Germany
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Hamburg, Germany
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Hanover, Germany
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Heilbronn, Germany
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Magdeburg, Germany
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Riesa, Germany
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Ulm, Germany
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Würzburg, Germany
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Bologna, Italy
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Piacenza, Italy
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Kashiwa-shi, Japan
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Kōtō City, Japan
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Osaka, Japan
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Tokyo, Japan
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Toyama, Japan
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Ube, Japan
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Yokohama, Japan
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Hwasun, South Korea
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Seongnam, South Korea
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Seoul, South Korea
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Barcelona, Spain
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Elche, Spain
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Girona, Spain
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Madrid, Spain
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Pamplona, Spain
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Vigo, Spain
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Zaragoza, Spain
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Birmingham, United Kingdom
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Cottingham, United Kingdom
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London, United Kingdom
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Manchester, United Kingdom

Conditions

Explore the condition pages connected to this study.

METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA