LUNG CANCERS

This study tests a new experimental drug, KESONOTIDE™, in people with advanced solid tumors like prostate, breast, lung, ovarian, pancreatic, skin cancer, or glioblastoma. The main goal is to check the drug's safety and find the right dose. About 80 adults will take part in two p…

This study tests a new drug called AVZO-1418 in people with advanced solid tumors that have spread. The main goals are to find a safe dose and see if the drug can shrink tumors. About 480 adults will take part in this first human trial.

This early-phase trial tests a new treatment for people with advanced solid tumors (sarcoma, lung cancer, or melanoma) that have not responded to first-line therapy. The treatment involves taking a patient's own immune cells, modifying them in the lab to better recognize and atta…

This study is testing a new blood test to find early-stage lung cancer in heavy smokers who have no symptoms. Researchers will collect blood samples from 350 current or former smokers aged 30-80, including some with known lung cancer and some without. The goal is to see if the te…

This study tests a new robotic technology (ssRAB) to take tissue samples from lung nodules. Current methods work only about 70% of the time, sometimes requiring riskier procedures. The robot uses sensors to guide a thin tube more accurately to the nodule. 100 adults with lung nod…

This study is testing an 8 to 12 week exercise program for people who have or had cancer. The program includes supervised exercise classes, either online or in person, twice a week. The goal is to help participants increase their physical activity and reduce cancer-related sympto…

This study compares standard palliative radiation to a newer, more focused technique that delivers a higher dose of radiation while sparing the esophagus. The goal is to improve or maintain quality of life for people with lung tumors that cannot be cured. About 141 adults with in…

This study tests a special program designed to help lung cancer survivors living in rural areas feel better and manage their health. About 300 survivors will either join the program or receive standard information. The goal is to see if the program improves quality of life and he…

This study compares two types of nerve blocks (erector spinae vs. intercostal) using a long-lasting anesthetic to control pain after lung surgery. About 120 adults having video-assisted lung procedures will be enrolled. The goal is to see which block provides better pain relief a…

This study looks at whether a traditional Chinese herbal medicine, called modified Bufei decoction, can reduce common symptoms like cough, tiredness, and shortness of breath in people aged 65 and older who have had lung cancer surgery. About 174 participants will receive either t…

This study compares two common sedation methods—conscious sedation and general anesthesia—used during a lung biopsy procedure called radial endobronchial ultrasound. The goal is to see which method helps doctors get a clearer diagnosis for lung nodules. About 306 adults with smal…