New radiation technique aims to ease lung cancer symptoms with fewer side effects
NCT ID NCT06794125
First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 2 times
Summary
This study compares standard palliative radiation for lung tumors with a newer, more focused technique that delivers a higher dose while sparing the esophagus. The goal is to improve or maintain quality of life by better controlling symptoms and reducing side effects. About 141 adults with lung cancer needing symptom relief will participate.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 141 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Intrathoracic tumour requiring palliative radiation, either for palliation of symptoms or prevention of progression that is expected to cause symptoms in the next 6 months (in the judgement of the enrolling investigator) * Willingness and ability to provide informed consent * Eastern Cooperative Oncology Group performance status 0-3 * Age 18 years or older * Prior or planned systemic treatment (chemotherapy, immunotherapy, targeted agents) is permissible at the discretion of the treating medical oncologist * Concurrent palliative radiotherapy to other metastatic sites is permissible at the discretion of the treating radiation oncologist. * Life expectancy greater than 3 months Exclusion Criteria: * Prior thoracic radiotherapy which, in the opinion of the treating of radiation oncologist, precludes the delivery of further thoracic radiotherapy. If there has been prior thoracic radiotherapy, a composite of all RT plans must be created, and the dose constraints herein must still be met. An allowance for 10 percent repair is permitted if at least 12 months have passed between the prior radiotherapy and the trial protocol specified radiotherapy. * Serious medical comorbidities which, in the opinion of the treating radiation oncologist, preclude the delivery of radiotherapy. This includes interstitial lung disease. * Pregnant or lactating women * Inability to attend the full course of radiotherapy or planned follow-up visits
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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British Columbia Cancer Agency Center for the Southern Interior
RECRUITINGKelowna, British Columbia, V1Y5L3, Canada
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Horizon Health New Brunswick
RECRUITINGSaint John, New Brunswick, Canada
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London Health Sciences Center Research Institute (Formerly Lawson Research Institute)
RECRUITINGLondon, Ontario, N6A 4L6, Canada
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Waterloo Regional Health Network
RECRUITINGWaterloo, Ontario, Canada
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