Ancient herbal mix may soothe cough and fatigue in elderly lung cancer patients
NCT ID NCT06674252
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a traditional Chinese medicine formula called modified Bufei Decoction can reduce cough, fatigue, and shortness of breath in elderly patients who have had lung cancer surgery. About 174 participants will receive either the herbal granules or a placebo twice daily for 28 days. Researchers will measure symptom changes using a standard symptom scale.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Jiawei Bufei Tang granules (a traditional Chinese herbal formula)
- What this could lead to
- If it works, this could offer a natural option to reduce common post-surgery symptoms like cough and fatigue in older lung cancer patients.
- What could go wrong
- This is an early phase 2 trial with only 174 participants, so results may not apply broadly. The herbal mixture is complex and its active ingredients are not fully understood.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 174 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with postoperative lung cancer who have clear histological or cytological diagnosis. * Age ≥ 65 years old, both male and female are eligible. According to the MDASI-TCM scale evaluation, any of the three symptoms of cough, fatigue, and shortness of breath should score ≥ 4 points, or the sum of the three should score ≥ 6 points. * The heart function is basically normal; ALT/AST is within 2 times the normal value; SCr is within the normal range. Traditional Chinese medicine syndrome differentiation is characterized by deficiency of both lungs and kidneys. Exclusion Criteria: * Patients with severe pulmonary infections. ⑵. Patients with mental illness. ⑶. Patients with depression.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing cancer hospital
RECRUITINGBeijing, Beijing Municipality, 100142, China
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Beijing cancer hospital
RECRUITINGBeijing, Beijing Municipality, 100142, China
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