LOCALLY ADVANCED BREAST CANCER
Clinical trials for LOCALLY ADVANCED BREAST CANCER explained in plain language.
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New breast cancer drug challenger enters final testing phase
Disease control OngoingThis study compares a new drug, RPH-051, to an existing drug called Perjeta for people with HER2-positive breast cancer that has spread or cannot be removed by surgery. Both drugs are given together with trastuzumab and docetaxel as the first treatment. The main goal is to see if…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE3 • Sponsor: R-Pharm • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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New combo shows promise against tough breast cancer
Disease control OngoingThis study tests a new drug called onvansertib combined with standard chemotherapy (paclitaxel) in people with triple-negative breast cancer that has spread to other parts of the body. About 50 adults with advanced disease are participating to see if the combination is safe and c…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Antonio Giordano, MD • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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New hope for hard-to-treat breast cancer: experimental combo enters phase II
Disease control OngoingThis study tests a new drug called BNT327, given together with chemotherapy, for people with advanced triple-negative breast cancer that has spread. The goal is to see if the combination is safe and shrinks tumors. About 83 adults will take part, receiving one of two dose levels …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated May 26, 2026 03:05 UTC
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Radiation before chemo: a new hope for High-Risk breast cancer?
Disease control OngoingThis study tests whether giving a small, focused dose of radiation to the tumor before standard chemotherapy can improve treatment for people with high-risk or locally advanced breast cancer. The radiation is meant to 'prime' the immune system to fight the cancer better. About 40…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Can a simple biopsy spot hidden cancer after chemo?
Knowledge-focused OngoingThis study looks at how well sentinel lymph node biopsy finds leftover cancer cells after chemotherapy in women with locally advanced breast cancer. About 162 women who had chemotherapy and whose lymph nodes seemed cancer-free will get this biopsy. The goal is to see how often th…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC