LOCALLY ADVANCED BREAST CANCER
Clinical trials for LOCALLY ADVANCED BREAST CANCER explained in plain language.
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New drug shows promise against tough breast cancers
Disease control CompletedThis study tested an experimental drug called U3-1402 (patritumab deruxtecan) in 121 people with advanced or metastatic breast cancer. The goal was to see if the drug could shrink tumors and to check for side effects. The drug is designed to target cancer cells directly, and the …
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: SCRI Development Innovations, LLC • Aim: Disease control
Last updated May 26, 2026 03:13 UTC
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New hope for BRCA breast cancer: triple-drug combo shows promise in early trial
Disease control CompletedThis early-phase trial tested a combination of three drugs—olaparib, palbociclib, and fulvestrant—in 9 people with advanced, hormone receptor-positive breast cancer who also have BRCA1 or BRCA2 mutations. The main goal was to see if the combination is safe and to measure how long…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New combo shows promise in slowing advanced breast cancer
Disease control CompletedThis study tested whether adding the drug samuraciclib to standard hormone therapy (fulvestrant) works better than fulvestrant alone for people with a certain type of advanced breast cancer (HR-positive, HER2-negative). The trial included 60 adults whose cancer had worsened despi…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE2 • Sponsor: Carrick Therapeutics Limited • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New combo shows promise against tough breast cancer
Disease control CompletedThis study tested a new two-drug combination (samuraciclib and elacestrant) in 49 adults with a specific type of advanced breast cancer (HR+/HER2-). The goal was to see if the combination is safe and can slow down the cancer's growth. Participants had already tried other treatmen…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Carrick Therapeutics Limited • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Breast cancer patients may prefer treatment at home
Symptom relief CompletedThis study looked at whether people with HER2-positive breast cancer prefer getting their medication at home or in the hospital. 346 participants received a combination of two drugs (pertuzumab and trastuzumab) as a shot under the skin. The main goal was to see which setting they…
Matched conditions: LOCALLY ADVANCED BREAST CANCER
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC