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New drug cocktail shows promise for BRCA breast cancer

NCT ID NCT03685331

First seen Nov 21, 2025 · Last updated Apr 30, 2026 · Updated 21 times

Summary

This early-phase study tested a combination of three drugs (olaparib, palbociclib, and fulvestrant) in 9 people with a specific type of advanced breast cancer linked to BRCA gene mutations. The main goal was to check if the combination is safe and to see how long it keeps the cancer from growing. Participants had hormone receptor-positive, HER2-negative cancer that had spread or couldn't be removed by surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.