JUVENILE IDIOPATHIC ARTHRITIS

This study is testing a drug called olokizumab in children and teens (ages 2 to 18) with active juvenile idiopathic arthritis, a condition that causes joint pain and swelling. The main goal is to see how the drug moves through the body and to check its safety and effectiveness. A…

This study looks at the long-term safety and effectiveness of the drug baricitinib for children aged 1 to 17 with juvenile idiopathic arthritis (JIA). About 190 kids who have already taken baricitinib in a previous study will continue treatment to see how well it controls their a…

This study monitors the safety and effectiveness of the drug Cosentyx in Korean patients with three conditions: hidradenitis suppurativa (painful skin boils), pediatric plaque psoriasis (scaly skin patches in children), and juvenile idiopathic arthritis (childhood arthritis). Abo…

This study tests a drug called sarilumab in children aged 1 to 17 with systemic juvenile idiopathic arthritis, a type of arthritis that causes body-wide inflammation. The goal is to find the best dose and see if it safely controls the disease. About 51 participants will receive t…

This study looks at whether a Mediterranean diet can improve arthritis in children by changing the bacteria in their guts. Fifty-four kids with juvenile idiopathic arthritis will follow the diet for 8 weeks, with an option to continue for 4 more weeks. Researchers will collect st…

This study tests an experimental oral medication, upadacitinib, in children aged 1 to 17 with systemic juvenile idiopathic arthritis (sJIA), a rare and serious form of arthritis that can affect the whole body. About 90 participants will receive either upadacitinib or the standard…

This study is testing an oral medication called filgotinib in 10 children and teens aged 8 to 17 who have juvenile idiopathic arthritis (JIA). The goal is to see how the drug moves through the body and whether it is safe and tolerable. Participants must have moderately to severel…

This study aims to create a new, objective way to measure pain in children with juvenile idiopathic arthritis, lupus, or fibromyalgia. Researchers will collect data from 90 participants over one year to see if this pain measurement can help doctors choose the right treatment fast…

This study looks at how children with juvenile idiopathic arthritis (JIA) experience pain. Researchers will measure pain responses to heat, cold, and pressure, and collect information through questionnaires and saliva or blood samples. The goal is to better understand what causes…

This study looks at whether a walking test called the Dynamic Gait Index can be used to assess walking difficulties in children with juvenile idiopathic arthritis (JIA). Researchers will compare walking, balance, and pain in 52 children with JIA and healthy children aged 8–16. Th…

This study is creating a tool to help doctors diagnose and choose treatments for autoimmune diseases. Researchers will analyze blood and other samples from 500 children with autoimmune conditions and healthy children to find patterns in genes and proteins. The goal is to better u…