JUVENILE IDIOPATHIC ARTHRITIS

This study tested whether adding leflunomide to the standard drug methotrexate helps children with severe, hard-to-treat arthritis. Fifty children were split into two groups: one received both drugs, the other only methotrexate. Researchers tracked joint pain, swelling, and daily…

This study tested whether a weekly injection of abatacept, given for 24 weeks, could prevent juvenile idiopathic arthritis (JIA) from spreading to more joints or causing eye inflammation. 121 children with mild JIA (affecting 4 or fewer joints) took part. The goal was to see if t…

This study looked at the long-term safety of the drug tofacitinib in children with juvenile idiopathic arthritis (JIA). About 300 kids who had already taken tofacitinib in earlier studies continued taking it to see how safe it was over time. The main goal was to track side effect…

This study looked at 62 children with juvenile idiopathic arthritis whose disease was inactive. Researchers tested whether slowly reducing and then stopping their biologic medication was as safe and effective as staying on the full dose for 24 weeks. The goal was to see if taperi…

This study looked at the long-term safety of the drug tocilizumab (RoActemra/Actemra) in children with a type of juvenile arthritis. Seven children from France who finished a previous study received the drug every 4 weeks for up to 2 years. The main goal was to track any side eff…

This study looked at whether adding a probiotic (VSL#3) to standard treatment helps children with juvenile idiopathic arthritis (JIA). 51 children aged 1 to 7 with specific types of JIA took part. Researchers measured disease activity and changes in gut bacteria to see if the pro…

This study looked at two ways to help teenagers with Juvenile Idiopathic Arthritis (JIA) exercise: one with a physiotherapist in person and online, and another using a personalized mobile app. Both groups wore smart watches to track activity. The goal was to see if the mobile app…

This study looked at 126 children with juvenile idiopathic arthritis to find the best dose of the drug etanercept. Researchers measured drug levels in the blood and checked how well the arthritis was controlled. The goal was to tailor the dose to each child for better results and…

This study tested whether coaching sessions are practical for young people (ages 16-18) with rheumatic diseases like juvenile arthritis as they move from pediatric to adult rheumatology care. Researchers enrolled 26 participants and measured how many agreed to join, attended sess…

This completed study looked at two new blood markers (Calprotectin and Serum Amyloid Protein) in 20 children with juvenile arthritis and related inflammatory diseases. The goal was to see if these markers could help doctors track disease activity and flares better than standard t…

This study tested whether a transition coach could help 16-17 year olds with Juvenile Idiopathic Arthritis or Inflammatory Bowel Disease move from pediatric to adult healthcare. 27 teens took part in a coaching program to build self-management skills. The main goal was to see if …