JUVENILE IDIOPATHIC ARTHRITIS

This study is monitoring the safety and real-world effectiveness of an existing drug, Cosentyx, in patients with three chronic inflammatory conditions: hidradenitis suppurativa (painful skin lumps), pediatric plaque psoriasis, and juvenile arthritis. It will observe about 76 pati…

This study is testing whether following a Mediterranean-style diet for 8-12 weeks can help improve arthritis symptoms in children. Researchers want to see if the diet works by changing the mix of bacteria in the gut. The study will enroll 54 children with arthritis to see if this…

This study follows children with juvenile arthritis who have already taken baricitinib in previous trials. It aims to check the long-term safety and effectiveness of continuing this medication. The research involves about 190 participants aged 1 to 17 years old who will keep taki…

This study is testing a medication called filgotinib in children and teenagers with juvenile idiopathic arthritis (JIA). The main goals are to see how the drug behaves in the body, if it's safe, and if kids can tolerate it. It's an early-phase study for children aged 8 to 18 whos…

This study is testing how well and how safe the drug upadacitinib is for children and teenagers (ages 1 to under 18) with a rare and serious form of childhood arthritis called systemic juvenile idiopathic arthritis (sJIA). It will compare upadacitinib to another existing treatmen…

This study aims to find the right dose of an injected medication called sarilumab for children and teenagers (ages 1-17) with a severe form of juvenile arthritis. It will test how the drug moves through the body, its safety, and if it helps control the disease. The study includes…

This study aims to see if a specific walking test is a reliable tool for assessing mobility in children with juvenile idiopathic arthritis (JIA). Researchers will compare how 52 children with JIA and healthy children perform on tasks like walking, turning, and climbing stairs. Th…

This study aims to understand why children with juvenile arthritis experience pain. Researchers will compare pain sensitivity in children with arthritis to healthy children using simple tests like pressure and cold water. The goal is to learn more about how pain works in this con…

This study aims to create better tools for diagnosing and choosing treatments for children with rare autoimmune and inflammatory diseases. Researchers will analyze blood and tissue samples from 500 children to find molecular patterns linked to their conditions. The goal is to pre…