ISCHEMIC HEART DISEASE

This study tests a new, very thin stent coated with a drug (sirolimus) in 500 heart disease patients who also take blood thinners. These patients have a high risk of bleeding when they need a stent. The new stent may allow for a shorter course of antiplatelet drugs, potentially r…

This study tests a new type of heart stent that slowly dissolves over time. It is designed for people with long blockages in their coronary arteries. The goal is to see if the stent is safe and works well to keep arteries open and reduce heart problems over one year. About 100 pa…

This study is checking if a medical device called Essential Pro is safe and works as intended for people with narrowed or blocked heart arteries. About 100 patients who already received the device as part of their routine care will be followed. Researchers will track heart-relate…

This study is checking how safe and effective the SUPRAFLEX CRUZ stent is for people with blocked heart arteries. About 508 adults who already got the stent as part of their routine care will be followed for a year. Researchers will track serious heart problems like heart attacks…

This study is testing a long stent (a small mesh tube) to treat long blockages in the heart's arteries. The goal is to see if using one long stent is safe and works well for these difficult blockages. About 1,039 adults with coronary artery disease will take part. The main focus …

This study compares two treatments for people with a completely blocked heart artery (chronic total occlusion) that causes reduced blood flow to the heart muscle. About 1,560 participants will either receive a stent to open the blockage plus medication, or medication alone. The g…

This study tests whether giving a carbohydrate drink before heart bypass surgery can improve insulin sensitivity and recovery in people with type 2 diabetes. Researchers will measure insulin tolerance, inflammation, and surgical outcomes in 50 participants. The goal is to see if …

This study looks at 600 people who had a major heart attack and have other blockages that are not severe enough to need immediate treatment. Some of these blockages are unstable and could cause another heart attack. The trial compares two approaches: placing stents in these unsta…

This study follows over 2,000 patients with coronary artery disease who received a device called Sequent Please Neo during routine care. Researchers want to confirm the device is safe and works well by tracking major heart problems like heart attacks or the need for repeat proced…

This study is checking how well a new drug-coated heart stent (Coroflex ISAR NEO) works and how safe it is in 3,000 people with narrowed heart arteries. Participants get the stent as part of their regular care, and doctors will track heart-related events like heart attacks or the…

This study tests a new type of heart stent made from magnesium that slowly dissolves over time, compared to a permanent metal stent. The goal is to see if the dissolvable stent is safe and works as well for people with blocked heart arteries. About 1,859 adults with coronary arte…

This study tests artificial intelligence (AI) tools that help doctors interpret heart ultrasound images more accurately and quickly. The goal is to see if AI can speed up the diagnosis of conditions like genetic heart muscle disease, blocked arteries, and cardiac amyloidosis. Up …

This study looks at whether a common heart procedure (using the wrist artery to treat blocked heart vessels) can damage nerves in the hand. Researchers will check 400 patients for signs of carpal tunnel syndrome or other nerve problems. The goal is to understand the risk and help…

This study tests a mobile app called GeriKit to gather more information about older adults (75+) with ischemic heart disease. Researchers want to see if the app helps them better understand patients' health and outcomes, like hospital readmission or quality of life. About 150 peo…

This study tests a new type of MRI that can show how heart cells process energy in people with ischemic heart disease. About 15 participants will undergo this special scan along with standard imaging. The goal is to see if this technique can tell healthy from damaged heart tissue…

This study looks at whether opening a blocked artery more than 12 hours after a heart attack helps patients. It involves 150 adults who are stable and had a heart attack 12 to 36 hours earlier. Researchers will use MRI scans to measure how much heart muscle is saved and how well …

This study looks at whether a special map called a dynamic coronary roadmap can help doctors perform heart artery pressure tests more quickly. About 226 adults with narrowed heart arteries will be randomly assigned to get the map or not during their procedure. The main goal is to…

This study aims to make sure lab tests, equipment, and procedures used in research on obesity, diabetes, heart disease, and bone disorders are accurate and give consistent results. It will involve up to 100 healthy volunteers and people with these conditions, aged 18 to 100. The …

This study aims to improve how we detect and understand heart disease using a new type of MRI that looks at the heart's microscopic structure. Researchers will compare these advanced scans with standard tests and blood work in 1,000 adults, both healthy volunteers and those with …

This study looks at whether a special heart scan (coronary CT angiography) is better than standard follow-up care for high-risk patients who have had a stent placed to open blocked arteries. About 3,500 adults aged 19 and older with complex heart conditions will be enrolled. The …

This study follows 2000 adults with suspected coronary artery disease who have had special imaging or pressure tests inside their heart arteries. Researchers will track major heart events like death, heart attack, or repeat procedures over many years. The goal is to learn which f…