ISCHEMIC HEART DISEASE

This study is testing a new catheter system designed to help doctors safely open completely blocked heart arteries. It will be used in 115 adults who still have chest pain or other symptoms despite taking heart medication. The main goals are to see if the device can successfully …

This study is a registry that tracks how well the ihtDEStiny drug-coated heart stent performs in everyday medical practice. It will follow 400 patients with blocked heart arteries who receive this stent during a standard angioplasty procedure. The main goal is to see how often pa…

This early-stage study is testing whether transplanting lab-grown heart muscle cells can help people with severe heart failure caused by previous heart attacks. Ten participants will receive either a low or high dose of these cells, then take immune-suppressing drugs to prevent r…

This study aimed to test whether a gene therapy called VM202RY could help the heart heal after a serious heart attack. The treatment involved injecting the therapy directly into the heart muscle of eligible patients to try to improve blood flow and heart function. The trial was d…

This study is testing whether a one-year course of a dietary supplement called spermidine can help older adults with heart disease. Spermidine is a natural compound found in foods like whole grains and nuts. Researchers will check if it improves heart function, muscle mass, physi…

This study compares two similar drug-coated stents used to prop open blocked heart arteries. It will enroll 550 patients in China who need this procedure to see if the newer Resolute Onyx stent performs as well as the established Resolute Integrity stent. Researchers will track p…

This study is testing whether using a temporary heart pump during high-risk stent procedures helps prevent serious complications like heart failure or death. It involves 300 patients with severe coronary artery disease and weakened heart muscle who face higher risks during these …

This study aims to see how three different methods for treating severely hardened heart arteries affect tiny blood vessel flow. It will enroll 30 patients with coronary artery disease who need a stent. Researchers will compare lithotripsy (shockwaves), super-high pressure balloon…

This study is testing the safety and effectiveness of a specific drug-coated heart stent (the Medtronic Resolute Onyx) in Chinese patients with blocked coronary arteries. About 591 participants who are eligible for a standard artery-opening procedure (angioplasty) will receive th…

This study is testing whether using a detailed, high-resolution imaging scan called Optical Coherence Tomography (OCT) during emergency heart attack treatment leads to better long-term results for patients. It will compare OCT-guided procedures to the current standard method that…

This study is testing how well a new, detailed ultrasound scan (called UFR) can identify serious blockages in heart arteries. It compares the new scan's results to a standard diagnostic method in 112 patients with suspected heart disease. The goal is to see if this new imaging te…

This study aimed to test a new support program for adults hospitalized with heart disease. The program would automatically screen patients for social needs like food or housing insecurity and connect them electronically to local community resources. The goal was to see if address…

This study observes how doctors in Spain use injectable blood thinners during heart stent procedures. Researchers will track 717 real-world patients to see which medications are used and monitor their safety and effectiveness. The goal is to understand current medical practices a…

This study is a large registry that aims to better understand how problems with the heart's smallest blood vessels affect the health of people with coronary artery disease. It will observe 1,003 adult patients who are already undergoing standard heart artery testing and procedure…

This study aims to understand why some women experience chest pain and heart stress despite having clear major heart arteries. Researchers are examining 206 women with stable chest pain to see if tiny blood vessel problems, platelet activity, or inflammation might be the cause. T…