INFECTION

This study tests whether a home-based rapid response team can safely reduce the number of days adults with suspected infection spend in the hospital. About 500 participants are randomly assigned to either standard hospital care or a home assessment and treatment pathway. The goal…

This study tests whether an iodine-coated barrier dressing applied before surgery can reduce bacteria around heart devices like pacemakers. About 390 adults having a device replacement or upgrade will be randomly assigned to get the dressing before or after the incision. The goal…

This study looks at how well the antibiotic aztreonam-avibactam works in real hospital settings for patients with serious infections caused by multidrug-resistant bacteria. About 100 critically ill adults will be followed to see if the drug clears the infection without the need f…

This study looks at whether a new DNA sequencing technology (Nanopore) can better identify infections in broken bones compared to standard lab tests. Researchers will collect bone samples from 100 adults with fracture-related infections and compare the results from both methods. …

This study looks at whether adding antibiotic powder directly into the joint during hip or knee replacement surgery can lower infection rates compared to using IV antibiotics alone. About 1,800 adults having a first-time or aseptic revision replacement are taking part. Researcher…

This study looks back at 4,000 patients who had a viral infection in the brain or spinal cord. Researchers want to see how symptoms and outcomes differ between children, adults, and people with weakened immune systems. The goal is to help doctors diagnose and treat these infectio…

This study will enroll 40 children aged 8-18 with Familial Mediterranean Fever (FMF) to see if infections trigger disease flares. Participants will use a mobile app to record symptoms like fever, cough, or sore throat, and any FMF attacks. The goal is to better understand the con…

This study aimed to see if a computer program could predict how long patients would stay in a home hospital program. Researchers used data from past patients to train the program. The study was withdrawn before enrolling any participants, so no results are available.

This study tracks 120 patients who receive a left ventricular assist device (LVAD), a mechanical heart pump. Researchers want to see how often infections happen after surgery and how the immune system changes. The goal is to find clues that could help predict and prevent infectio…

This study aimed to see if a computer program could predict potassium levels in the blood using a simple heart monitor. Researchers planned to use data from patients treated at home. The study was withdrawn before any participants were enrolled, so no results are available.