IMMUNODEFICIENCY
Clinical trials for IMMUNODEFICIENCY explained in plain language.
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Radical transplant trial aims to halt devastating new disease
Disease control Recruiting nowThis study is testing whether a stem cell transplant from a donor can successfully treat VEXAS syndrome, a rare and serious condition that causes severe inflammation and blood problems. Adults with severe VEXAS who haven't responded to standard treatments will receive donor stem …
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New transplant trial aims to reset immune system in rare genetic disorder
Disease control Recruiting nowThis study is testing whether a stem cell transplant from a donor can treat GATA2 deficiency, a genetic condition that causes serious infections and blood cancers. Participants (ages 6-70) will receive chemotherapy and then donor stem cells to try to rebuild their immune system. …
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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New hope for vulnerable patients: study tests stronger COVID treatments
Disease control Recruiting nowThis study aims to find better COVID-19 treatments for people with weakened immune systems. Researchers are testing whether combining two antiviral drugs works better than using one alone, and whether extending treatment from 5 to 10 days helps clear the virus faster. The trial w…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: Calmy Alexandra • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Scientists test Double-Duty drug combo to knock out COVID in vulnerable patients
Disease control Recruiting nowThis study is testing if using two antiviral drugs together works better than one alone, and if taking the main drug for 10 days is better than 5 days, for people with weakened immune systems who get COVID-19. It aims to help these high-risk patients clear the virus faster and mo…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Scientists probe Parkinson's Drug's hidden immune side effects
Knowledge-focused Recruiting nowThis study aims to understand how the drug clozapine, used to treat psychosis in Parkinson's disease, affects the body's immune system over time. Researchers will follow 24 Parkinson's patients for a year, measuring their immune cell and antibody levels. The goal is to gather inf…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Hunting the genetic roots of rare immune diseases
Knowledge-focused Recruiting nowThis study aims to discover the specific genes that cause certain inherited immune disorders and understand how they affect health and family risk. It involves patients and their family members who have or are suspected of having these genetic conditions. Participants provide blo…
Matched conditions: IMMUNODEFICIENCY
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC