Immunodeficiency
Clinical trials for Immunodeficiency explained in plain language.
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Rewriting the code: a One-Time gene fix for a rare immune disease?
Cure By invitation onlyThis trial tests a one-time gene therapy for WHIM syndrome, a rare inherited immune disorder that causes severe infections. Doctors collect a person's own blood stem cells, use base editing to correct the faulty CXCR4 gene, and return the edited cells to the body. The goal is to …
Matched conditions: IMMUNODEFICIENCY
Phase 1/2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Cure
Last updated Sep 20, 2026 00:00 UTC
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New drug could make stem cell transplants safer for rare immune disorder
Disease control OngoingThis phase II trial tests whether a new drug called Briquilimab can make stem cell transplants safer for people with GATA2 deficiency, a rare genetic condition that weakens the immune system and raises the risk of infections and blood cancers. The study involves 13 participants a…
Matched conditions: IMMUNODEFICIENCY
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Holistic education study for stress withdrawn before starting
Knowledge-focused CancelledThis study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …
Matched conditions: IMMUNODEFICIENCY
Sponsor: Goddess Zena I. Jones • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC