HUMAN PAPILLOMAVIRUS INFECTION

This large study tests whether a single dose of the HPV vaccine protects against HPV infection and cervical cancer as effectively as the standard two doses. Nearly 28,000 girls aged 12–16 are taking part. If one dose works, it could make vaccination cheaper and easier, especially…

This study tests a program called PC TEACH that helps rural doctor's offices give more HPV vaccines to teens. HPV vaccines can prevent several cancers, but many rural teens miss out. The program coaches clinics on better ways to talk about and offer the vaccine. Researchers will …

This study tests a vaginal insert called ABI-2280 to see if it can clear persistent high-risk HPV infections in women aged 25 to 55. Participants have had HPV for at least a year with no serious cervical changes. The study checks safety and how well the insert works compared to a…

This study looks at whether giving the HPV vaccine to adults before they receive a kidney transplant can help their bodies build a strong immune response. After transplant, patients take drugs to prevent rejection, which weaken the immune system. The goal is to see if the vaccine…

This study compares the accuracy of self-collected vaginal samples versus doctor-collected cervical samples for HPV testing in 750 people referred for colposcopy or cervical procedures. The goal is to see if self-collection is a reliable, more comfortable option to increase scree…

This study compares the accuracy of HPV testing on self-collected vaginal samples versus samples collected by a doctor during a pelvic exam. About 500 people referred for colposcopy or cervical procedures will provide both types of samples. The goal is to see if self-collection i…

This study looks at whether women can collect their own vaginal samples for HPV testing instead of having a doctor collect them during a pelvic exam. About 500 people referred for colposcopy or cervical procedures will provide both a self-collected sample and a doctor-collected s…

This study looks at whether mailing self-sampling HPV test kits to Asian and Asian American women who are behind on screening can help them get tested for cervical cancer. About 111 women in Houston, Texas, who haven't had a Pap test in years will receive a kit to collect their o…

This study looks at ways to increase HPV vaccination among 1,200 young adults aged 18-26 in Texas. HPV can cause certain cancers, and the goal is to find the best methods to encourage people to start and finish the vaccine series. Participants are college students who have not ye…

This study looks at whether giving women a simple self-collection kit for HPV testing at Express Care clinics (which have evening and weekend hours) can increase the number of women who get screened for cervical cancer. About 500 women ages 30–63 who are overdue for screening wil…

This study follows thousands of women in Costa Rica who received the HPV vaccine years ago, plus a new group of unvaccinated women, to see how well the vaccine works over time. Researchers are checking for cervical cell changes, immune markers, and whether the vaccine might shift…

This study looks at whether testing men for HPV antibodies or HPV DNA in their blood can help find throat and anal cancers early. Researchers will follow 1,500 men who test positive for these markers to see how many develop cancer. The goal is to improve screening and catch these…

This study follows nearly 1,000 women from an earlier HPV vaccine trial to see how long their immune protection lasts—up to 20 years after getting 1, 2, or 3 doses. Researchers will test blood samples over time to measure antibody levels and check if any women lose protection. Th…