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One shot may be enough: major HPV vaccine trial could change global cancer prevention

NCT ID NCT03180034

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 30 times

Summary

This large study tests whether a single dose of the HPV vaccine works as well as the standard two doses to prevent HPV infection, which causes most cervical cancers. Over 27,000 girls aged 12 to 16 are taking part. If one dose is effective, it could make vaccination cheaper and easier, especially in countries with high cervical cancer rates.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Agencia Costarricense de Investigaciones Biomédicas (ACIB)

    Liberia, Guanacaste Province, 50101, Costa Rica

Conditions

The condition(s) this trial relates to.

cervical carcinoma human papilloma virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.