One shot may be enough: huge study tests Single-Dose HPV vaccine

NCT ID NCT03180034

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 23 times

Summary

This large study is testing whether a single dose of the HPV vaccine can protect against the virus that causes most cervical cancers. Over 27,000 girls aged 12-16 received either one or two doses. If one dose works, it could make vaccination cheaper and easier, especially in countries where cervical cancer is common and vaccine access is limited.

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Contacts and locations

Locations

  • Agencia Costarricense de Investigaciones Biomédicas (ACIB)

    Liberia, Guanacaste Province, 50101, Costa Rica

Conditions

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