HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New vaccine aims to train immune system against HPV cancers
Disease control Recruiting nowThis early-stage trial tests a new vaccine called Lenti-HPV-07 in 72 people with HPV-related throat or cervical cancer. The vaccine is designed to teach the body's immune system to attack cancer cells caused by HPV. The study checks if the vaccine is safe and whether it triggers …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Theravectys S.A. • Aim: Disease control
Last updated May 26, 2026 07:01 UTC
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Nasal vaccine combo shows promise against HPV throat cancer in early trial
Disease control Recruiting nowThis early-phase study tests a new nasal vaccine (WSK-IM05) combined with an immunotherapy drug (tislelizumab) given before surgery for HPV-positive throat cancer. About 9 participants will receive two cycles of the combination, then undergo surgery, followed by standard treatmen…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: West China Hospital • Aim: Disease control
Last updated May 26, 2026 07:01 UTC
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Supercharged immune cells take on HPV cancers
Disease control Recruiting nowThis study tests a new immunotherapy for people with advanced HPV-related cancers (cervical, throat, anal, and others). Doctors take a patient's own immune cells, add a special receptor to help them find and attack HPV-infected cancer cells, and give them back. The goal is to shr…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 26, 2026 06:59 UTC
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Could less radiation be just as effective for HPV+ throat cancer?
Disease control Recruiting nowThis study is testing whether a lower dose of radiation (30 Gy) can safely treat HPV-positive oropharyngeal cancer while reducing side effects. About 31 adults with this type of throat cancer will receive the reduced radiation along with standard chemotherapy. The main goal is to…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Sara Medek • Aim: Disease control
Last updated May 26, 2026 06:53 UTC
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Immune cells engineered to fight HPV tumors before standard care
Disease control Recruiting nowThis study tests whether a single dose of a patient's own genetically modified immune cells (E7 TCR-T cells) can shrink or eliminate HPV-related cancers before standard treatment like chemo-radiation or surgery. About 15 adults with advanced HPV-positive cancers (e.g., cervical, …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 26, 2026 06:51 UTC
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Could less radiation be enough? new trial adjusts treatment midway for HPV-Positive throat cancer
Disease control Recruiting nowThis study tests whether people with HPV-positive throat cancer can safely receive lower doses of radiation if their tumors shrink quickly during treatment. About 120 participants will have their treatment plan adjusted based on early scans and blood tests. The goal is to see if …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated May 26, 2026 06:46 UTC
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Blood test may spare some HPV throat cancer patients from unnecessary radiation
Disease control Recruiting nowThis study is for people with HPV-related throat cancer who have had or will have surgery to remove the tumor. Researchers will use a blood test to look for tiny bits of cancer DNA (ctDNA) to see if the cancer is likely to come back. The goal is to find out if some patients can s…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 06:46 UTC
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New combo therapy aims to boost immune attack on HPV head and neck cancer
Disease control Recruiting nowThis study tests a new drug called CUE-101, alone or with pembrolizumab, in 30 people with newly diagnosed, advanced HPV-16 head and neck cancer that cannot be removed surgically. The goal is to see if these treatments can boost the immune system to fight the cancer before standa…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated May 26, 2026 06:45 UTC
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Could less radiation be enough for HPV throat cancer?
Disease control Recruiting nowThis study is testing whether a lower dose of radiation can still control HPV-positive throat cancer while reducing side effects. About 111 people with this type of cancer will receive the reduced radiation and be followed for at least two years. The goal is to see if the cancer …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: University of California, Irvine • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New drug cocktail aims to shrink Hard-to-Treat head and neck tumors
Disease control Recruiting nowThis study tests whether combining two drugs, sacituzumab govitecan and cetuximab, can shrink tumors in people with advanced head and neck cancer that has gotten worse after first-line therapy. About 40 adults with certain types of head and neck cancer will receive the drug combi…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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Blood test may spare throat cancer patients from unnecessary radiation
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test can tell which throat cancer patients can safely skip radiation after surgery. About 61 people with HPV-related throat cancer will have their blood tested before and after surgery. If the test is negative after surgery, they won't g…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 26, 2026 06:51 UTC