HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug duo takes on HPV-driven head and neck cancer in phase 2 trial
Disease control CompletedThis study tested whether adding an experimental immunotherapy (PDS0101) to the approved drug pembrolizumab (Keytruda) can shrink tumors or slow cancer growth in people with a specific type of head and neck cancer linked to HPV16. The trial enrolled 95 adults whose cancer had ret…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: PDS Biotechnology Corp. • Aim: Disease control
Last updated May 26, 2026 09:03 UTC
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New hope for HPV-linked head and neck cancer: early trial tests targeted therapy
Disease control CompletedThis early-phase study tested a new drug called CUE-101, alone or with pembrolizumab, in 80 adults with HPV16-positive head and neck cancer that had spread or returned. The main goals were to check safety and find the right dose. Researchers also looked at how well the drug shran…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Cue Biopharma • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Spit test could spot HPV throat cancer early
Diagnosis CompletedThis study tested a new saliva test that looks for DNA from HPV and a related virus to detect HPV-positive throat cancer. Researchers compared results from 360 people—some with cancer and some without—to see how accurate the test is. The goal is to develop a simple, non-invasive …
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated May 26, 2026 09:07 UTC
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Simple blood test may spot hidden cancer after surgery
Diagnosis CompletedThis study tested a new blood test (liquid biopsy) to see if it can find small amounts of cancer left behind after surgery in people with HPV-related head and neck cancer. 103 patients who had surgery to remove their cancer gave blood samples. The goal was to see if the test coul…
Matched conditions: HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Diagnosis
Last updated May 15, 2026 11:57 UTC