HPV INFECTION

This study looks at whether a smaller (one-fifth) dose of the HPV vaccine can still trigger a strong immune response in adults aged 27 to 45. Researchers are comparing two types of HPV vaccines and two ways of giving the shot (into the skin or into the muscle). The goal is to see…

This study looks at whether two doses of the HPV vaccine (Gardasil 9) can protect women aged 16 to 45 as well as the standard three-dose schedule. About 352 women from Boston Medical Center are taking part. Researchers will measure antibody levels in the blood to compare immune r…

This study in Tanzania tests whether giving a single dose of the HPV vaccine to boys aged 14-18, in addition to the existing girls' vaccination program, reduces HPV infections in the community. About 10,400 people across 26 communities will take part. Researchers will compare HPV…

This study tests the 9-valent HPV vaccine in 700 men living with HIV to see if it can prevent long-lasting oral HPV infections that can lead to cancer. Participants receive the vaccine or a placebo and are followed for up to four years. The goal is to stop HPV types linked to thr…

This study tests a game-based program designed for families with children aged 11-14 who have not yet received the HPV vaccine. The goal is to see if the game is easy to use and helps parents decide to vaccinate their children. About 131 families will participate, and researchers…

This study tests a web-based program called ORCHID designed to improve mental health and help women with HIV stay in care. It involves 30 aging women of color who also have HPV. Participants learn skills to build positive emotions and resilience through 8 online sessions.

This study looks for the best way to screen for cervical cancer in women living with HIV. About 1,000 women from Latin American countries will provide samples and have a detailed exam. The goal is to find which test most accurately identifies precancerous changes that need treatm…

This study looks at how well vaginal self-sampling works for detecting high-risk HPV in women aged 30-65 who have immune-mediated inflammatory diseases like lupus or Sjögren's syndrome. Researchers will measure HPV infection rates and track changes over one year. The goal is to m…

This study looks at how common high-risk HPV is in transgender people and whether self-collected samples (from the vagina, anus, urine, or mouth) work as well as clinician-collected ones. About 100 transgender men and women will take their own samples and answer a survey about co…