HIV PREVENTION

This study tests a program called MEPS that uses a mobile app, peer mentors, and small rewards to help people recently released from jail get HIV testing, PrEP (a daily pill to prevent HIV), and substance use treatment. About 300 people in California will take part. The goal is t…

This study tests a new approach called PAC-Man to help prevent HIV from passing from mother to child during pregnancy and breastfeeding. About 2,400 mothers and infants in Malawi will take part. The goal is to see if this model improves early infant testing and viral load checks …

This study tests a data dashboard that helps clinics in Alabama track and improve access to PrEP, a daily pill that prevents HIV. Researchers will work with 7 clinics to see if the dashboard helps more Black patients get PrEP and reduces racial gaps in prevention. The study invol…

This study looks at whether adding a peer health coach to re-entry services can help people with a history of justice involvement learn about and start taking PrEP, a daily pill that prevents HIV. About 100 adults who use Unlocking Doors services in Dallas will take part. The goa…

This study focuses on helping cisgender women and transgender individuals who are at risk for HIV to start and continue taking PrEP, a daily pill that prevents HIV infection. Researchers will survey about 175 participants to understand their preferences for different PrEP options…

This study looks at the safety of two HIV prevention methods—an injectable drug (CAB-LA) and daily pills (oral PrEP)—in pregnant and breastfeeding women in Malawi. About 621 women who are already using or start PrEP during pregnancy will choose their preferred option and be follo…

This study is tracking how HIV is prevented in over 6,500 people across 23 French clinics. It looks at HIV testing, STI and hepatitis screening, and the use of prevention medicines like PrEP and PEP. The goal is to better understand who uses these services and how effective they …

This study tests a program to help Black women in Baltimore start taking PrEP, a medication that prevents HIV. The program addresses challenges like intimate partner violence and racism that can make it harder to get PrEP. Researchers will enroll 300 Black women who are HIV-negat…

This study tests a new way to prevent HIV by giving a long-acting injectable medication called lenacapavir to people who are unhoused or unstably housed in Los Angeles County. A mobile health van brings the shots directly to shelters, encampments, and community centers. The goal …

This study looks at whether giving HIV self-test kits and counseling to HIV-negative women after childbirth can help them and their male partners learn their HIV status and start PrEP (prevention) or antiretroviral therapy (treatment). About 120 women and their partners in South …

This study looks at how a single dose of two F/TAF tablets (a common HIV prevention pill) works in the body over 14 days. It involves 24 healthy volunteers to measure drug levels inside cells. The goal is to see if a higher single dose could be used for HIV prevention.

This study tests an online program called UPDOs Protective Styles to help Black women in the southeastern US learn about and start using PrEP, a daily pill that prevents HIV. About 1,000 women from 32 beauty salons will either use the program (videos, blogs, and telehealth) or re…

This study tests a combination program to help adolescent girls and young women (ages 15-24) at high risk of HIV in Uganda start and stick with PrEP, a daily pill that prevents HIV. The program includes HIV education, support from peers who have used PrEP, and financial help like…

This study tests a program called Treat4All that helps people reduce heavy drinking and improve HIV prevention or treatment. About 160 adults receiving STI care in Lilongwe, Malawi, who report recent heavy drinking will take part. Half will get the Treat4All program, and half wil…

This study aims to make HIV and STI testing easier for men who have sex with men (MSM) in Baltimore by using a mobile van and online ads to reach them. Participants will either get help from a peer health navigator to connect to PrEP or HIV care, or just receive referrals. The go…

This study tests a culturally-tailored program offering long-acting injectable PrEP (lenacapavir) to 100 Latine gay, bisexual men, and transgender women in the southern U.S. The goal is to see if this community-delivered approach helps more people start and stay on PrEP compared …

This study tests a mobile health program designed to reduce HIV-related stigma and improve use of HIV prevention pills (PrEP) among young transgender women in Thailand. About 108 HIV-negative participants aged 18-29 who have had condomless sex will use the app and be followed for…

This study tests a text-message-based program to help trans girls and nonbinary youth (ages 14-18) prevent HIV. Participants receive messages and surveys on their phones to encourage HIV testing and use of PrEP (a daily pill that prevents HIV). The goal is to see if this approach…

This study looks at whether people with HIV can collect their own blood samples at home using a simple finger prick. The goal is to see if these self-collected samples are as good as those taken in a clinic for measuring drug levels. About 150 adults already on HIV treatment or p…

This study looks at whether adding conversations about sexual pleasure to existing harm reduction services helps men and transgender people who use drugs in Thailand. Researchers will use a tool called the Pleasuremeter to measure sexual satisfaction and willingness to discuss pl…

This study is testing a harm reduction service designed specifically for transgender women, transgender men, and non-binary people in Thailand who have used substances or engaged in chemsex in the past year. The service aims to increase uptake of HIV prevention medication (PrEP),…

This study talks to men who have sex with men and take part in chemsex (using drugs during sex) in Bangkok. Researchers want to understand the physical, mental, and social harms they face. The goal is to design a program led by hosts of chemsex parties to reduce risks like HIV, S…

This study talks to transgender people about their experiences with chemsex (using drugs during sex) to learn why they do it, the good and bad effects, and what kind of help they need. Researchers will also ask healthcare workers and community leaders about barriers to providing …