HIDRADENITIS SUPPURATIVA

This study tests a new drug called brivekimig for people with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes boils and tunnels. The trial will compare different doses of brivekimig to a placebo over about 48 weeks to see if it reduces skin …

This study tests a new drug called SAR445399 for people with moderate to severe hidradenitis suppurativa (HS), a skin condition causing painful lumps. About 144 adults will receive either the drug or a placebo for 32 weeks to see if it reduces the number of abscesses and inflamed…

This study monitors the safety and effectiveness of the drug Cosentyx in Korean patients with three conditions: hidradenitis suppurativa (painful skin boils), pediatric plaque psoriasis (scaly skin patches in children), and juvenile idiopathic arthritis (childhood arthritis). Abo…

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition causing painful lumps under the skin. About 550 adults will use either the cream or a placebo for several weeks to see if it reduces lumps and prevents flare-up…

This study tests a daily pill called upadacitinib for people with moderate to severe hidradenitis suppurativa (painful lumps under the skin) who haven't improved with standard treatments. About 1,328 adults and teens will receive either the drug or a placebo for up to 104 weeks. …

This study tests a new drug, LAD191, in 200 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition causing boils and tunnels. The goal is to see if LAD191 can reduce the number of inflamed lesions better than a placebo. Participants will receive ei…

This study tests a new drug called remibrutinib for people with moderate to severe hidradenitis suppurativa, a condition causing painful lumps under the skin. About 555 adults and teens will take either one of two doses of the drug or a placebo for 68 weeks. The goal is to see if…

This early-stage trial tests a new drug called HB0043 in 15 adults with moderate to severe hidradenitis suppurativa, a painful skin condition. The drug targets two proteins involved in inflammation to reduce flare-ups. The main goal is to check safety and see if it helps control …

This study follows 142 Canadian adults with moderate-to-severe hidradenitis suppurativa (a chronic skin condition causing painful lumps) who are prescribed secukinumab as part of their routine care. Researchers will track changes in disease severity over 12 months using a standar…

This study tests a drug called bimekizumab in children and teenagers aged 9 to 17 with moderate to severe hidradenitis suppurativa, a painful skin condition that causes boils. The main goal is to see how the drug moves through the body and if it is safe. About 40 participants wil…

This study tests a daily pill called ritlecitinib for people with moderate to severe hidradenitis suppurativa (HS), a condition causing painful red skin lumps. About 240 adults who haven't been helped by antibiotics will receive either the drug or a placebo for 16 weeks. Research…

This study tests a new oral drug, zasocitinib, for moderate to severe hidradenitis suppurativa (HS), a skin condition causing painful, deep bumps and abscesses. About 90 adults will receive either the drug or a placebo for 4 months, then all will get the drug for up to 8 more mon…

This study tests two doses of a drug called remibrutinib against a placebo in 555 people aged 12 and older with moderate to severe hidradenitis suppurativa (HS), a condition causing painful lumps under the skin. The main goal is to see if the drug reduces the number of inflamed n…

This study tests a medicated foam applied to the skin for people with hidradenitis suppurativa, a condition that causes painful lumps. The foam, called roflumilast, may help control symptoms when used alone for mild cases or alongside other treatments for more severe disease. Res…

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition that causes painful bumps under the skin. About 550 adults with HS for at least 6 months will use the cream or a placebo for several weeks. The goal is to see i…

This study explores whether Botox injections can calm the inflammation and pain of hidradenitis suppurativa (HS), a chronic skin condition. Researchers believe that blocking certain nerve signals may reduce the immune response that causes HS flares. The study will enroll 20 adult…

This early-stage study tests a cream called ruxolitinib on 24 people with hidradenitis suppurativa, a painful skin disease. The main goal is to check safety and how the drug moves through the body. Participants apply the cream to affected skin areas for a set time.

This study tests an investigational drug called lutikizumab for people with moderate to severe hidradenitis suppurativa (HS), a chronic skin disease causing painful lumps and scars. About 1,280 adults and teens will receive either lutikizumab or a placebo for 16 weeks, then all w…

This study looks at how alopecia areata, vitiligo, and hidradenitis suppurativa affect the daily lives of teens and adults. Researchers will survey nearly 2,800 people worldwide to measure symptoms, hair loss, skin changes, and quality of life. The goal is to better understand th…

This study follows 250 Italian adults with moderate to severe hidradenitis suppurativa (HS) who are starting secukinumab. Researchers will collect data on how well the drug reduces skin abscesses and tunnels over time, as well as treatment patterns and healthcare costs. The goal …

This early study tests whether taking a capsule of healthy gut bacteria (microbiota transplant) can change the gut microbiome in 16 adults with hidradenitis suppurativa, a chronic and painful skin condition. The goal is to see if these gut changes affect skin bacteria and possibl…

This study is gathering information from 1,000 people with hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will track symptoms, genetics, and other health data to create a better classification system and identify potential new treatment…

This observational study will follow 800 adults undergoing soft tissue reconstruction where doctors use Myriad™, a sheep-derived material. The goal is to monitor safety and healing times, such as wound closure and complication rates. Participants must be 18 or older and willing t…

This study looks at how much of the drug bimekizumab passes into the breast milk of mothers who are already taking it for conditions like psoriasis or arthritis. About 20 breastfeeding women will provide milk samples over several weeks. The goal is to understand possible exposure…

This study is creating a large registry of 3000 people with hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will collect medical information and blood samples over time to learn what causes HS and how it progresses. The goal is to develo…

This study collects skin samples from 175 people with hidradenitis suppurativa, a painful inflammatory skin disease. The samples are stored in a biorepository for future research. The goal is to help scientists better understand and potentially find new treatments for this and ot…

This study collects skin samples from people with conditions like acne, eczema, and psoriasis, as well as healthy volunteers. The goal is to analyze genes and other markers to better understand what causes these inflammatory skin diseases. No treatment is given; it is purely for …