New study monitors Real-World impact of secukinumab on painful skin condition
NCT ID NCT07282015
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 142 Canadian adults with moderate-to-severe hidradenitis suppurativa who are prescribed secukinumab as part of their regular care. Researchers will track changes in disease severity over 12 months using a standard scoring system. The goal is to understand how well the treatment works in everyday practice and to monitor safety.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 142 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Canadian patients diagnosed with moderate-to-severe HS and treated with secukinumab as per routine clinical practice
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients must give written, signed, and dated informed consent before any information is collected and any study-related activity is performed. 2. Adult patients at the time of informed consent signature. 3. Patients with the diagnosis of moderate-to-severe HS, as determined by the dermatologist. 4. Patients who have been newly prescribed secukinumab as part of routine clinical care according to the approved Canadian PM. The decision to prescribe secukinumab must be made prior to,and independent of, study participation. First treatment with secukinumab must occur no more than 7 days (≤7 days) prior to Baseline visit. 5. Patients who can understand written and spoken Canadian English or French. Exclusion Criteria: 1. Any medical or psychological condition in the treating physician's opinion that may prevent the patient from study participation. 2. Patients who have any contraindications to treatment with secukinumab, as defined in the Canadian PM. 3. Patients who have had any prior exposure to secukinumab (i.e., \>7 days prior to the baseline visit).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
15 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Novartis Investigative Site
RECRUITINGCalgary, Alberta, T2J 7E1, Canada
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Novartis Investigative Site
RECRUITINGCalgary, Alberta, T3E 0B2, Canada
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Novartis Investigative Site
RECRUITINGWinnipeg, Manitoba, R3M 3Z4, Canada
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Novartis Investigative Site
RECRUITINGFredericton, New Brunswick, E3B 1G9, Canada
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Novartis Investigative Site
RECRUITINGSt. John's, Newfoundland and Labrador, A1E 1V4, Canada
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Novartis Investigative Site
RECRUITINGCobourg, Ontario, K9A 4J9, Canada
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Novartis Investigative Site
RECRUITINGHamilton, Ontario, L8P4B4, Canada
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Novartis Investigative Site
RECRUITINGLondon, Ontario, N6H 5L5, Canada
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Novartis Investigative Site
RECRUITINGMarkham, Ontario, L3P 1X3, Canada
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Novartis Investigative Site
RECRUITINGMississauga, Ontario, L4W 0C2, Canada
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Novartis Investigative Site
RECRUITINGRichmond Hill, Ontario, L4C 9M7, Canada
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Novartis Investigative Site
RECRUITINGToronto, Ontario, M4E 1R7, Canada
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Novartis Investigative Site
RECRUITINGSaint-Jérôme, Quebec, J7Z 7E2, Canada
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Novartis Investigative Site
RECRUITINGSherbrooke, Quebec, J1L 0H8, Canada
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Novartis Investigative Site
RECRUITINGSaskatoon, Saskatchewan, S7N0N5, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can an injected drug calm the painful flares of hidradenitis suppurativa?
- Nanobody drug tested against painful skin condition
- Can a mediterranean diet tame hidradenitis suppurativa?
- Can we predict the path of chronic skin disease?
- Can a pill that degrades IRAK4 tame autoimmune inflammation?
- Could childhood trauma fuel skin inflammation?