Hidradenitis suppurativa

Researchers are testing a drug called sonelokimab in adults with moderate to severe hidradenitis suppurativa, a chronic skin condition that causes painful lumps and abscesses. The trial compares sonelokimab, given by injection, with a placebo and with adalimumab, an existing trea…

This phase 3 trial is testing the long-term safety of bimekizumab, a drug that targets inflammation, in 658 people with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful boils. Participants who completed a previous study will receive bimek…

Researchers are testing LT-002-158, an oral drug that degrades IRAK4, a protein involved in inflammation. This first-in-human trial gives the drug to healthy volunteers to check its safety, tolerability, and how the body processes it. The study also looks at how food affects drug…

This study looks at whether secukinumab can keep hidradenitis suppurativa (a painful skin condition) under control over the long term. It includes 703 adults who already completed a year of treatment with secukinumab. Researchers will measure how long the response lasts and monit…

This study tests a new drug called eltrekibart in 352 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition causing abscesses and inflammation. Participants receive either the drug or a placebo for about 62 weeks. The goal is to find a safe and ef…

This study tested a drug called sonelokimab, given as a shot under the skin, in 422 adults with moderate to severe hidradenitis suppurativa (a painful skin condition causing boils and abscesses). Participants were randomly assigned to receive either the drug or a placebo for up t…

This study tests whether anifrolumab, an antibody drug, can reduce skin abscesses and nodules in people with hidradenitis suppurativa (HS). Fifteen adults with moderate-to-severe HS will receive the drug intravenously over 24 weeks. The main goal is to see if at least half of par…

This study compares two oral drugs, apremilast and acitretin, to see which works better for moderate-to-severe hidradenitis suppurativa, a painful skin condition. About 70 adults take one of the two pills twice daily for 12 weeks. The main goal is to measure how much the disease …

This study tested a drug called sonelokimab in 418 adults with moderate to severe hidradenitis suppurativa, a skin condition that causes painful lumps and abscesses. Participants received either the drug or a placebo injection for 16 weeks. The goal was to see if sonelokimab redu…

This Phase 3 trial tested bimekizumab, a drug that targets inflammation, in 509 adults with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful abscesses and tunnels. Participants received either bimekizumab or a placebo over 16 weeks. The m…

This study tested a drug called bimekizumab in 505 adults with moderate to severe hidradenitis suppurativa, a chronic skin condition that causes painful lumps. The main goal was to see if the drug reduces the number of inflamed lumps by at least half after 16 weeks, compared to a…

This study tested an injectable drug called AVTX-009 in 253 people with moderate to severe hidradenitis suppurativa, a chronic skin condition causing painful lumps. Participants received either the drug or a placebo every 2 or 4 weeks. The goal was to see if the drug could reduce…

This phase 2 study tested a new drug called SAR442970 in 86 adults with moderate to severe hidradenitis suppurativa, a chronic skin condition causing painful lumps. The drug is a Nanobody that targets two inflammatory proteins. Researchers compared it to a placebo to see if it co…

This study tested an experimental drug called ATI-450 in 95 people with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful lumps. The goal was to see if the drug reduces the number of abscesses and inflamed nodules compared to a placebo ove…

This study tested whether tofacitinib, a drug already approved for arthritis, is safe and helpful for immune-related skin conditions in people with Down syndrome. 47 adolescents and adults with Down syndrome and skin issues like eczema or psoriasis took the drug. Researchers chec…

This study looked at the long-term safety and effectiveness of the drug spesolimab for adults with hidradenitis suppurativa (HS), a painful skin condition. Participants who had already completed a previous spesolimab trial received injections every two weeks for two years. The go…

This study tested whether spesolimab, a drug already approved for another skin condition, can help people with moderate to severe hidradenitis suppurativa (HS), a painful skin disease that causes abscesses and tunnels. 209 adults participated, receiving either spesolimab or a pla…

This study tested whether spesolimab, an anti-inflammatory drug, can reduce painful lumps and abscesses in adults with moderate to severe hidradenitis suppurativa. Fifty-two participants were randomly assigned to receive either spesolimab or a placebo for about 3 months. Doctors …

This phase 2 trial tested a drug called imsidolimab (ANB019) in 149 people with hidradenitis suppurativa, a chronic skin condition causing painful abscesses and nodules. Participants received either the drug or a placebo to see if it could reduce the number of inflamed lesions. T…

This study looks at whether a simple home exercise program can improve strength, endurance, and quality of life for people with hidradenitis suppurativa (HS), a painful skin condition. Researchers will have 86 adults with HS follow a video-guided exercise routine 3-4 days a week.…

This study tests whether a special 1726nm laser can safely reduce the painful bumps and inflammation caused by hidradenitis suppurativa (HS). Eight adults with mild to moderate HS will receive laser treatment on affected areas like armpits or groin. The main goal is to see if at …

This study involved 324 adults with conditions like Crohn's disease, arthritis, or psoriasis who switched from a standard to a higher-concentration form of adalimumab (AVT-02). Researchers measured injection site pain and how well patients stuck with their treatment over 180 days…

This study tested whether a special bioelectric dressing can improve healing after a surgical procedure called de-roofing for hidradenitis suppurativa (HS), a chronic skin condition. Twelve adults with HS had two wounds treated: one with the bioelectric dressing and one with stan…

This study tested whether a 6-week online mindfulness course could improve quality of life for people with hidradenitis suppurativa (HS), a chronic skin condition that causes painful boils. Thirty-seven adults with HS took part. Half attended weekly mindfulness classes and did gu…

This study looked at skin samples from 20 people with hidradenitis suppurativa (HS) who had surgery. Researchers measured different inflammatory proteins in the lab to understand what drives the disease. The goal was to learn more about how inflammation works in HS, not to test a…

This study surveyed 67 adults with hidradenitis suppurativa (HS) to better understand how the condition affects their quality of life. Researchers also tested a new tool that lets patients rate their own disease severity using photos. The goal is to improve how doctors and patien…