HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

This study is testing a new treatment for adults with high-risk or hard-to-treat blood cancers like leukemia. The treatment involves a radioactive antibody designed to target cancer cells, followed by a stem cell transplant from a partially matched family donor. The main goals ar…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1, PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control

Last updated Apr 03, 2026 14:42 UTC

Double-Action flu attack: new combo therapy trial aims to protect most vulnerable

This study is testing if giving two antiviral drugs together (baloxavir and oseltamivir) works better than the standard single drug (oseltamivir) to treat severe influenza. It is for people with blood cancers or who have had a stem cell transplant, as their weakened immune system…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Apr 03, 2026 14:41 UTC

Special goat milk could protect cancer patients after transplant

This early-stage study is testing whether drinking milk from genetically engineered goats can help prevent a dangerous complication called graft-versus-host disease (GVHD) in blood cancer patients receiving a donor stem cell transplant. The milk contains a human enzyme called lys…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control

Last updated Apr 02, 2026 14:57 UTC

Stem cell trial offers hope for Chemotherapy-Damaged hearts

This study is testing whether stem cells from a donor's bone marrow can help control heart failure in people whose hearts were weakened by certain chemotherapy drugs. Researchers will compare two different ways of giving the cells (through an IV or directly into the heart) agains…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Apr 02, 2026 14:57 UTC

Experimental stem cell therapy tested for critical COVID-19 patients

This study is testing whether stem cells from umbilical cord blood can help control severe COVID-19 pneumonia. The trial will involve 70 hospitalized adults with moderate to critical pneumonia, comparing stem cell infusions against standard care. Researchers want to see if these …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 31, 2026 12:12 UTC

New cell therapy tested for Life-Threatening transplant complication

This early study is testing whether adding special cells from donated umbilical cord blood to the standard drug ruxolitinib works better than the drug alone. It aims to help cancer patients (ages 12-80) who develop a severe, steroid-resistant immune reaction called graft-versus-h…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 30, 2026 14:31 UTC

Scientists test 'Supercharged' immune cells against deadly viruses in vulnerable patients

This early-stage study is testing whether specially modified immune cells can safely help control serious viral infections in cancer patients with weakened immune systems. Researchers are collecting a patient's own T-cells, genetically engineering them to better target specific v…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 30, 2026 14:31 UTC

Lab-Grown immune cells deployed to fight virus in vulnerable patients

This early-stage study is testing a new treatment for adenovirus infections in people with weakened immune systems, such as cancer patients. Doctors are giving patients specially grown immune cells (T-cells) from healthy donors that are trained to attack the adenovirus. The main …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 30, 2026 14:31 UTC

Radiation 'Rescue' attempted for failing cancer immunotherapy

This study is testing if targeted radiation can help control cancer that has spread and started growing again after treatment with immunotherapy drugs. It will involve about 230 adults with metastatic solid tumors or blood cancers. Researchers aim to see if this 'salvage' radiati…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 27, 2026 12:40 UTC

New hope to avoid breathing tubes for cancer patients in crisis

Prevention Recruiting now

This study is testing if a special oxygen mask, called non-invasive ventilation, is better than standard high-flow oxygen at helping cancer patients with sudden, severe breathing problems. The main goal is to see if the mask can reduce the need for doctors to place a breathing tu…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control

Last updated Mar 20, 2026 14:47 UTC

One blood test for many cancers? study aims to find out

Diagnosis Recruiting now

This study aims to collect blood and tissue samples to help develop a single blood test that can detect many different cancers early. Researchers will enroll 2,000 people, including those with cancer and those without, to create a reference set for testing. The goal is to validat…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: Alliance for Clinical Trials in Oncology • Aim: Diagnosis

Last updated Mar 30, 2026 14:28 UTC

New hope to shield vulnerable kids from dangerous virus after transplant

This study is testing whether a drug called letermovir can prevent a serious viral infection called cytomegalovirus (CMV) in children and teenagers who have received a stem cell transplant. After a transplant, patients' immune systems are very weak, making them highly vulnerable …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Prevention

Last updated Mar 30, 2026 14:31 UTC

Brain training meets medicine in fight against Chemo's painful side effect

This study is testing whether combining a brain-training therapy called neurofeedback with a medication (duloxetine) works better than either treatment alone for relieving nerve pain caused by chemotherapy. About 380 cancer survivors with this type of pain will be assigned to rec…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief

Last updated Apr 03, 2026 14:42 UTC

Cancer patients battle insomnia: therapy vs. nutrition education in major sleep study

This study aims to find out which of two non-drug approaches works better to reduce insomnia in cancer patients undergoing treatment. Researchers are comparing a brief behavioral therapy program designed for cancer-related insomnia against a healthy eating education program. The …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE3 • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief

Last updated Mar 30, 2026 14:34 UTC

Can writing your worries away ease cancer stress?

This study is testing if a simple writing exercise can help cancer survivors manage stress, which can be made worse by events like the COVID-19 pandemic. About 414 adult cancer survivors will be randomly assigned to either write about their personal experiences or about neutral t…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief

Last updated Mar 30, 2026 14:30 UTC

Clot-Busting drug tested to relieve cancer Patients' severe breathlessness

This early study is testing whether alteplase, a drug that dissolves blood clots, can help cancer patients breathe easier. It focuses on patients who have a build-up of fluid around their lungs that won't drain properly through a permanent catheter, causing severe shortness of br…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief

Last updated Mar 25, 2026 14:07 UTC

Sticker rewards help young cancer patients stay active during treatment

This study is testing whether a reward-based exercise program can help children and young adults with cancer stay active during a stem cell transplant. Participants earn stickers for walking and other activities, which they can trade for rewards. Researchers want to see if this a…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief

Last updated Mar 24, 2026 12:02 UTC

New hope for cancer patients struggling to eat: major trial tests common drug against standard treatment

This study compares two medications—olanzapine and megestrol acetate—to see which works better at improving appetite and preventing weight loss in people with advanced cancer. Researchers will enroll 360 patients who have lost weight and have poor appetite due to their cancer. Pa…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief

Last updated Mar 13, 2026 15:05 UTC

Study probes Radiation's hidden cost: memory loss in cancer patients

This study aims to understand how whole brain radiation therapy affects memory, thinking, and quality of life in patients with blood cancers like lymphoma and leukemia. Researchers will follow 100 patients for up to 5 years, using standard memory tests, questionnaires, and brain …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Apr 03, 2026 20:57 UTC

Cancer researchers track treatment side effects to improve patient care

This study aims to better understand the side effects that occur in cancer patients receiving anti-VEGF therapies and how these side effects might relate to treatment effectiveness. Researchers will review medical records of 170 patients with blood cancers or solid tumors who are…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Apr 03, 2026 20:56 UTC

Massive study launched to map proton therapy side effects

This study collects detailed information about side effects experienced by cancer patients receiving proton radiation therapy. Researchers will follow 5,000 patients to understand both short-term and long-term effects, aiming to predict risks and improve safety for future patient…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Apr 01, 2026 14:42 UTC

Scientists track viruses to unlock cause of devastating transplant lung disease

This study aims to understand if respiratory viruses cause a serious lung disease called bronchiolitis obliterans syndrome (BOS) in people who have received a donor stem cell transplant. Researchers will follow 250 patients at risk for or already diagnosed with BOS for up to two …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused

Last updated Apr 01, 2026 14:42 UTC

Study probes Pandemic's hidden toll on young cancer survivors

This study aims to understand how the COVID-19 pandemic impacted the mental, financial, and social well-being of adolescent and young adult cancer patients and survivors. Researchers will survey about 600 participants to measure their stress, healthcare use, and life disruptions …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Apr 01, 2026 14:41 UTC

Doctors unite to create common language for prostate cancer care

This study aims to get expert doctors to agree on the most important information that should be consistently recorded in prostate cancer patient charts. A small panel of specialists will complete several rounds of surveys to reach a consensus. The goal is to create a standard rep…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Mar 30, 2026 14:32 UTC

Massive cancer study maps 12,000 tumors to find perfect treatments

This study analyzes cancer patients' tumor tissue and blood samples to identify specific genetic changes in their cancer. The goal is to create a detailed database of cancer mutations and use that information to match patients with the most relevant treatment options and clinical…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Mar 30, 2026 14:29 UTC

Can video calls train doctors to give better comfort care to dying patients?

This study is testing if a special online training program (called Project ECHO) can help doctors and nurses in rural and underserved areas provide better comfort and symptom care (palliative care) for people with advanced cancer. It will measure if patients' quality of life and …

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Mar 30, 2026 14:28 UTC

Doctors track data to Fine-Tune powerful cancer combo

This study collects information from patients with blood cancers who receive two advanced treatments: CAR-T cell therapy and radiation therapy. By reviewing medical records and imaging scans, researchers aim to understand how these treatments work together and which patients bene…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Mar 20, 2026 14:48 UTC

Doctors surveyed nationwide on Pandemic's lasting impact on lung care

This study is a nationwide survey asking lung doctors how their practices changed during the COVID-19 pandemic. Researchers want to learn how hospitals adapted their staffing, procedures, and outpatient care. The goal is to use this information to guide better responses to future…

Matched conditions: HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM

Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused

Last updated Mar 19, 2026 14:55 UTC

Scientists investigate if your gut bacteria could make cancer treatment more effective