HEMATOLOGIC MALIGNANCIES

This study looked at the long-term safety of an oral chemotherapy drug (azacitidine) in people with blood cancers. It enrolled 5 patients who had already taken the drug in earlier studies and were still benefiting from it. The main goal was to track any side effects that occurred…

This study tested a less intense bone marrow transplant for people with blood cancers who couldn't find a perfectly matched family donor. It used partially matched donors who were not first-degree relatives. The goal was to see if this approach could reduce severe side effects li…

This study looked at 50 patients who needed a stem cell transplant but had antibodies that could attack the donor cells. Before transplant, they received a blood purification treatment called protein A immunoadsorption to remove those antibodies. The goal was to see if this appro…

This study tested a three-drug combination (VIP152, venetoclax, and prednisone) in 8 adults with aggressive non-Hodgkin lymphomas that had not responded to or returned after prior treatment. The main goals were to check safety and find the best dose. Participants took pills at ho…

This study tested whether the drug tildrakizumab can help prevent graft-versus-host disease (GVHD) in people receiving a stem cell transplant for blood cancers. Fifty-one adults took part. The goal was to see if the drug could improve survival without severe GVHD or cancer relaps…

This study looked at 60 blood cancer patients who had a stem cell transplant and later developed a serious fungal infection called mucormycosis. Researchers compared cases before COVID-19 (2015-2020) and during the pandemic (2020-2024) to see how the virus, new tests, and treatme…

This study tested a program to help older adults (age 60+) with blood cancers discuss and document their healthcare wishes while they are in the hospital. 41 patients took part, and the program was found to be feasible, with most patients completing the planning session. The goal…