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New drug combo may make cord blood transplants safer for blood cancer patients

NCT ID NCT03434730

First seen Jun 02, 2026 · Last updated Jun 09, 2026 · Updated 1 time

Summary

This study tested whether adding the drug tocilizumab to standard care could reduce the risk of graft-versus-host disease (GVHD) after a cord blood transplant in adults with blood cancers. GVHD is a serious complication where donor cells attack the patient's body. Tocilizumab blocks a protein linked to inflammation, which is high after transplant. The study enrolled 46 participants and measured how long it took for GVHD to develop within the first 100 days.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm Hodgkin Disease Leukemia Leukemia, Myeloid, Acute Lymphoma, Non-Hodgkin Myelodysplastic Syndromes Myelodysplastic-Myeloproliferative Diseases Myeloproliferative Disorders Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.