HELICOBACTER PYLORI INFECTION
Clinical trials for HELICOBACTER PYLORI INFECTION explained in plain language.
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New hope for hard-to-treat stomach infections: rifabutin combo tested
Disease control CompletedThis study tested whether a rifabutin-based triple therapy can effectively treat Helicobacter pylori infections that did not respond to previous treatments. 360 adults with confirmed H. pylori and prior treatment experience were randomly assigned to one of three rescue therapies.…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated May 26, 2026 12:10 UTC
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Could a simpler pill combo beat the standard h. pylori treatment?
Disease control CompletedThis study tested whether a two-drug combination (vonoprazan plus either amoxicillin or doxycycline) works as well as the standard four-drug bismuth quadruple therapy for eradicating H. pylori infection. About 579 adults with H. pylori took one of three 14-day treatments. The goa…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 26, 2026 12:09 UTC
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New stomach bug treatment shows promise in head-to-head trial
Disease control CompletedThis study tested two different drug combinations to treat Helicobacter pylori, a bacteria that can cause stomach ulcers and other issues. About 400 adults took either a two-drug therapy (tegoprazan and amoxicillin) or a four-drug therapy (including bismuth and furazolidone). The…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New Two-Drug combo may beat standard h. pylori treatment with fewer pills
Disease control CompletedThis study tested a simpler 14-day treatment using two drugs (vonoprazan and amoxicillin) against a more complex standard therapy for H. pylori infection in 337 adults in Taiwan. The goal was to see if the simpler regimen works just as well, with fewer side effects and easier use…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Fu Jen Catholic University Hospital • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New drug combo aims to wipe out stomach bug in phase 3 trial
Disease control CompletedThis study tested a new three-drug combination (DWP14012-based triple therapy) against a standard treatment to see if it can safely and effectively eliminate Helicobacter pylori, a bacteria that can cause stomach ulcers. 461 adults with confirmed H. pylori infection took part. Th…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE3 • Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New hope for stubborn stomach bug: study tests better antibiotic combo
Disease control CompletedThis study tested two different antibiotic combinations in 782 adults with a hard-to-treat H. pylori infection that is resistant to the common antibiotic clarithromycin. Participants had peptic ulcers, H. pylori-related stomach inflammation, or a low-grade stomach lymphoma. The g…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: NA • Sponsor: Kangdong Sacred Heart Hospital • Aim: Disease control
Last updated May 26, 2026 11:59 UTC
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New drug combo shows promise for stubborn stomach bug, but side effects common
Disease control CompletedThis study tested a 14-day treatment with minocycline and metronidazole for people whose H. pylori infection did not clear with previous treatments. The new combination worked as well as the standard therapy, but over half of participants had side effects. The goal was to find a …
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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Which bismuth combo works best for stomach bug? large study reveals real-world results
Disease control CompletedThis study looked at how well different bismuth-containing four-drug combinations work to cure H. pylori infection in 1,730 adults aged 18-70 who had never been treated before. Researchers compared success rates and side effects across the different regimens. The goal was to find…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Yueyue Li • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New Two-Drug combo may beat standard Four-Drug regimen for stomach bug
Disease control CompletedThis study tested whether a simpler two-drug combination (tegoprazan and amoxicillin) works better than the standard four-drug treatment for eradicating H. pylori, a bacteria that can cause stomach ulcers. 370 adults with H. pylori infection participated. The goal was to see if t…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Zhang Xiaofeng,MD • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Herbal mix boosts antibiotic power against stomach bug?
Disease control CompletedThis study tested whether adding a traditional Chinese herbal formula (Banxiaxiexin decoction) to a standard two-drug antibiotic treatment works better for clearing H. pylori infection and easing stomach discomfort. 104 adults with both H. pylori and functional dyspepsia took par…
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE3 • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Which therapy wipes out stomach bug best? triple vs quadruple showdown
Disease control CompletedThis study tested two different 14-day treatments for H. pylori, a bacteria that causes stomach inflammation and ulcers. 752 adults in Pakistan were randomly assigned to either a triple therapy or a bismuth-based quadruple therapy. The goal was to see which treatment cleared the …
Matched conditions: HELICOBACTER PYLORI INFECTION
Phase: PHASE4 • Sponsor: Azfar Farogh • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Scientists map gut bugs in stomach infection and overgrowth combo
Knowledge-focused CompletedThis study looked at 42 adults with both H. pylori infection and small intestinal bacterial overgrowth (SIBO). Researchers used advanced DNA and chemical tests to map the gut bacteria and their metabolic byproducts. The goal was to better understand how these two conditions toget…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Zhongshan Hospital (Xiamen), Fudan University • Aim: Knowledge-focused
Last updated May 26, 2026 12:13 UTC
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Stomach bug treatment may change vaginal health, study finds
Knowledge-focused CompletedThis study looked at how standard treatment for H. pylori (a stomach infection) affects the natural bacteria in the vagina. Researchers followed 73 women, both before and after they took antibiotics and other medicines for H. pylori. They found that the treatment can change the t…
Matched conditions: HELICOBACTER PYLORI INFECTION
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC