HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) explained in plain language.
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Could a simple pacemaker tweak ease a major heart condition?
Disease control Recruiting nowThis study is testing whether programming a pacemaker to a personalized, slightly faster heart rate can help people with a specific type of heart failure feel better and stay out of the hospital. About 700 participants will have a pacemaker implanted and then be randomly assigned…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Disease control
Last updated Apr 03, 2026 20:40 UTC
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Smart watch aims to keep heart failure patients out of hospital
Disease control Recruiting nowThis study is testing whether a smartwatch-like device, combined with artificial intelligence, can help people with chronic heart failure stay healthier and avoid hospital trips. About 205 adults with stable heart failure will either use the device for six months or receive their…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: University of Salerno • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Doctors test Nerve-Zapping procedure for common heart condition
Disease control Recruiting nowThis study is testing whether a minimally invasive procedure that treats a specific nerve can help people with a common type of heart failure. About 150 participants will be randomly assigned to receive either the real nerve treatment or a simulated 'sham' procedure. Researchers …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Axon Therapies, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Heart rhythm battle: procedure vs. pills for double heart trouble
Disease control Recruiting nowThis pilot study is comparing two common treatment approaches for people who have both atrial fibrillation (an irregular heartbeat) and heart failure with preserved heart function. Participants will be randomly assigned to either have a catheter ablation procedure to try to resto…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Nova Scotia Health Authority • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New scans could crack the code on hidden heart failure
Diagnosis Recruiting nowThis study aims to see if advanced heart scans can better identify a tricky-to-diagnose type of heart failure where the heart pumps normally but is too stiff to fill properly. Researchers will enroll 40 people with symptoms like shortness of breath but an unclear diagnosis after …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Diagnosis
Last updated Mar 27, 2026 12:39 UTC
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Researchers probe hidden links between body composition and heart function
Knowledge-focused Recruiting nowThis study aims to understand how blood flow in the heart's smallest arteries and a person's body composition (like muscle and fat mass) relate to their ability to exercise. It will enroll 100 adults with a specific type of heart failure who have chest pain but no major artery bl…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Korea University Anam Hospital • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Major study launches to crack the code of a mysterious heart condition
Knowledge-focused Recruiting nowThis study aims to better understand why people develop a specific type of heart failure where the heart muscle is stiff. Researchers will observe 1,250 patients at a specialist clinic over five years, collecting health information and optional blood samples. The goal is to ident…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Manchester University NHS Foundation Trust • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Mobile MRI trucks hunt for silent heart failure in german cities
Knowledge-focused Recruiting nowThis study aims to find out how many people with risk factors like diabetes or high blood pressure have early, hidden heart failure without knowing it. Researchers will use mobile MRI trucks in five major German cities to screen 450 adults aged 40-69 who have no symptoms. The goa…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: German Heart Institute • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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First human test for new heart failure drug begins
Knowledge-focused Recruiting nowThis is an early-stage study to check the safety and tolerability of a new drug called VS-041 in people with a specific type of heart failure (HFpEF). It will involve 42 participants and will closely monitor for any side effects. The study will also measure changes in certain blo…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: PHASE1 • Sponsor: Vasa Therapeutics • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC