HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) explained in plain language.
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Nerve-Zapping catheter offers new hope for heart failure
Disease control Recruiting nowThis study tests a new catheter-based procedure that targets a nerve to help people with a type of heart failure called HFpEF. About 150 participants will receive either the procedure or a sham to see if it improves symptoms like shortness of breath and exercise ability. The goal…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Axon Therapies, Inc. • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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AI-Powered wearable aims to cut heart failure hospitalizations by 20%
Disease control Recruiting nowThis study is testing whether a special wearable device, guided by artificial intelligence, can help adults with chronic heart failure avoid emergency visits and hospital stays. About 205 participants will either wear the device for six months or receive standard care. The goal i…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: University of Salerno • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Heart failure and AFib: which treatment works better?
Disease control Recruiting nowThis study looks at two ways to treat atrial fibrillation (an irregular heartbeat) in people who also have heart failure with preserved or mildly reduced heart function. Participants will be randomly assigned to either a procedure called catheter ablation to restore normal rhythm…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Nova Scotia Health Authority • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Could a smarter pacemaker ease a common type of heart failure?
Disease control Recruiting nowThis study tests whether a pacemaker programmed to each person's needs can improve symptoms and outcomes for people with heart failure with preserved ejection fraction (HFpEF). About 700 adults with HFpEF will either receive personalized pacing or minimal/no pacing. The goal is t…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New imaging techniques aim to catch hidden heart failure
Diagnosis Recruiting nowThis study looks at whether advanced heart scans (echocardiogram and MRI) can improve diagnosis of heart failure with preserved ejection fraction (HFpEF), a condition where the heart is stiff but pumps normally. Standard tests often miss it, leaving many without proper treatment.…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Diagnosis
Last updated May 18, 2026 12:03 UTC
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Stent or sham? landmark trial tests heart failure fix
Symptom relief Recruiting nowThis study tests whether opening blocked heart arteries with stents can improve quality of life for people with a type of heart failure called HFpEF. 350 participants will be randomly assigned to receive either a real stent or a placebo procedure, and neither they nor their docto…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: PHASE2 • Sponsor: King's College London • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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New drug VS-041 tested for stiff heart condition
Symptom relief Recruiting nowThis early-stage trial tests the safety and tolerability of a new drug called VS-041 in 42 adults aged 50 and older with heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but is too stiff to fill properly. Researchers will monitor …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: PHASE1 • Sponsor: Vasa Therapeutics • Aim: Symptom relief
Last updated May 22, 2026 13:55 UTC
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Researchers launch major study to unravel mysteries of common heart condition
Knowledge-focused Recruiting nowThis study aims to understand why people develop a type of heart failure called HFpEF, which causes breathlessness and tiredness. Researchers will collect information from 1,250 patients attending a specialized clinic to identify new tests, treatments, and factors affecting life …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Manchester University NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Mobile MRI vans hunt for silent heart failure in german cities
Knowledge-focused Recruiting nowThis study aims to find out how many people in large German cities have early, symptom-free heart failure. Researchers will use a mobile MRI scanner, along with blood tests and quality-of-life surveys, to screen 600 adults who have risk factors like diabetes, high blood pressure,…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: German Heart Institute • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Heart fat linked to stiff heart? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether having more fat around the heart makes heart function worse in people with a type of heart failure called HFpEF. Researchers will use CT and MRI scans, blood tests, and other checks in 130 obese and non-obese patients. The goal is to understand the rol…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: University of Leicester • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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Heart failure mystery: why Can't patients exercise? new study seeks answers
Knowledge-focused Recruiting nowThis study looks at how tiny blood vessels in the heart and body composition (muscle vs. fat) affect exercise ability in people with a type of heart failure called HFpEF. Researchers will measure blood flow and muscle mass in 100 adults aged 20-80 who have chest pain or shortness…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: NA • Sponsor: Korea University Anam Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC