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Mobile MRI vans hunt for silent heart failure in city dwellers

NCT ID NCT07185100

Knowledge-focused Sponsor: German Heart Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will use a mobile MRI truck to screen 600 people in large German cities who have risk factors like diabetes, high blood pressure, or obesity but no heart failure symptoms. The goal is to find out how many have hidden (stage B) heart failure. Results will be compared to a similar rural study to see if city living makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a practical screening method to catch heart failure early in at-risk people, potentially preventing progression.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health, and results may not apply to other populations or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2036

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population from which the groups or cohorts will be selected are asymptomatic adults from the urban areas of Berlin, Cologne, Frankfurt (Main), Hamburg, and Munich with no history of heart failure who have one or more risk factor for developing heart failure. They are either volunteers or referred from local cardiologists.

Ages

40 to 69 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Asymptomatic subjects with: * chronic diabetes mellitus (known/diagnosed and/or antidiabetic medication and/or elevated HbA1C) and/or * renal impairment (known/diagnosed CKD and/or in laboratory CKD III° or higher) and/or * Hypertension (known/diagnosed and/or antihypertensive medication/treatment) and/or * Hypercholesterolaemia (known/diagnosed and/or antilipid medication/treatment) and/or * Obesity (known/diagnosed and/or BMI \> 30 (kg/m²)) and/or * Smoker (known/diagnosed and/or current/previous and/or medication/treatment) * Age 40-69 years * female or male or diverse sex * Ability to provide informed consent * Provision of Informed Consent Exclusion Criteria: * Inability to provide written informed consent * Diagnosed heart failure or previously detected reduced ejection fraction * General MRI exclusion criteria (pacemaker, defibrillator, intracranial aneurysm clips, metallic foreign bodies in the eyes) * Any MRI exclusion criteria not listed here, as determined by the MRI laboratory performing the procedure * Haemodynamically unstable participants (heart rate \< 45/min, systolic blood pressure \< 90 mmHg) * Claustrophobia * Sensorineural hearing loss of 30 dB or more and tinnitus * Acute mental disorders requiring therapy * In the presence of pregnancy

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Conditions

The condition(s) this trial relates to.

diastolic heart failure heart failure impaired renal function disease kidney failure Sprains and Strains

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure with preserved ejection fraction (hfpef) Renal dysfunction Stage B heart failure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Deutsches Herzzentrum der Charité

    RECRUITING

    Berlin, 13353, Germany

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