HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Clinical trials for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) explained in plain language.
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New hope for dialysis patients with heart failure?
Disease control CompletedThis study tested a drug called sacubitril/valsartan in 52 people on dialysis who also have a type of heart failure (HFpEF). The goal was to see if the drug improves heart function and is safe for this group. Participants were randomly assigned to receive the drug or standard car…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: PHASE4 • Sponsor: University Clinical Hospital Mostar • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New MRI scan could spot hidden heart problems without gadolinium
Diagnosis CompletedThis study tested a new MRI technique using a manganese-based contrast agent to measure how well heart cells take up manganese. It included 44 healthy volunteers and heart failure patients with preserved ejection fraction caused by hypertrophic cardiomyopathy or cardiac amyloidos…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Phase: PHASE2 • Sponsor: IC TARGETS AS • Aim: Diagnosis
Last updated May 22, 2026 13:54 UTC
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Heart failure drug use tracked in 13,660 remote monitoring patients
Knowledge-focused CompletedThis study reviewed the medical records of over 13,000 adults with chronic heart failure enrolled in a French remote monitoring program between 2021 and 2024. Researchers wanted to see how often doctors prescribed a type of medication called SGLT2 inhibitors, and whether factors …
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Satelia • Aim: Knowledge-focused
Last updated May 26, 2026 05:13 UTC
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Researchers check if Real-World data can replace clinical trials
Knowledge-focused CompletedThis study looked at over 11,000 people with type 2 diabetes and a certain type of heart failure to see if information from insurance claims could give the same results as a traditional drug trial. The goal was to learn when real-world data can be trusted to answer medical questi…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 05:06 UTC
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Heart failure risk prediction gets a boost from blood and imaging combo
Knowledge-focused CompletedThis study looked at medical records of 4,000 heart failure patients to see if combining routine blood tests (like NT-proBNP) with heart scan results (like fat density around the heart) could better predict who might die within a year. The goal is to improve personalized risk ass…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Brain pressure may trigger heart rhythm problems in heart failure
Knowledge-focused CompletedThis study looked at 309 older adults with a type of heart failure called HFpEF to understand why some develop atrial fibrillation (AFib), an irregular heartbeat. Researchers measured fluid pressure in the body and brain using ultrasound and found that higher pressure in the vein…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: Ankara Ataturk Sanatorium Training and Research Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Bike test sheds light on mysterious heart condition
Knowledge-focused CompletedThis study looked at 40 adults with a type of heart failure where the heart pumps normally but still causes symptoms. Researchers used a special exercise test on a bike to measure how the heart, lungs, and muscles work during activity. The goal was to better understand the condit…
Matched conditions: HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)
Sponsor: University of Ulster • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC