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Bike test could unlock mysteries of common heart condition

NCT ID NCT07394010

Knowledge-focused Sponsor: University of Ulster Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 40 people with heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but still causes symptoms. Researchers used a special exercise test on a bike to measure how the heart, lungs, and muscles work together during activity. The goal was to better understand the condition and find ways to improve diagnosis and personalized care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cardiopulmonary exercise test (CPET)
What this could lead to
If successful, this research could improve how doctors diagnose and personalize treatment for people with heart failure with preserved ejection fraction.
What could go wrong
This is a small, completed observational study, not a treatment trial. The findings may not apply to all patients and need further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jun 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients registered with the South Eastern Health and Social Trust (NHS), Northern Ireland, UK.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female * Age range between 18 - 80 years * Clinical suspicion of Heart failure with preserved ejection fraction * Ejection Fraction of ≥50% on the most recent Echocardiogram * Able to understand the performance of an exercise test and the ability to provide consent * Ability to undertake leg exercise without any impediment Exclusion Criteria: * • Hospital admission in the past 6 months * Unable to understand the performance of an exercise test * Unable to provide informed consent * Female subjects who are knowingly pregnant or believe they may be pregnant * Having an impediment preventing them from performing cycle ergometry * Contra-indication of CPET: acute myocardial infarction, unstable angina, uncontrolled arrhythmias, moderate or severe valvular disease, High-degree atrioventricular block, acute infection, acute endocarditis, myocarditis, uncontrolled asthma, and history of syncope.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure with preserved ejection fraction (hfpef)

Contacts and locations

Locations

  • Ulster University and Ulster Hospital

    Belfast, Middlesex, BT16 1RH, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.