HEALTHY VOLUNTEER

This study tests a new PET heart scan that uses 10 to 100 times less radiation than current methods. It involves 200 adults with known or suspected heart artery disease. Participants get a tiny dose of a radioactive tracer and are scanned for up to 3 hours to see if the images ar…

This early-stage study looks at how a new drug called ABBV-295 interacts with common birth control pills in healthy adult women who are overweight or obese. The main goal is to check for side effects and measure drug levels in the body. About 20 women will take part to help resea…

This early-stage study tests a single dose of ABBV-701 in about 100 healthy adults from Western and Asian backgrounds. The main goal is to check for side effects and measure how the drug moves through the body. Participants receive either the drug or a placebo, and no direct heal…

This early-stage study tests the safety of an experimental drug called D-2570 in 36 healthy volunteers. Participants receive either the drug or a placebo to see how the body handles it and whether any side effects occur. The goal is to gather safety information, not to treat any …

This early-stage study in 40 healthy adults aims to understand how the experimental drug ABBV-8736 moves through the body when given as a shot under the skin compared to an infusion into a vein. Researchers will measure the drug's levels in the blood, safety, and any side effects…

This study screens up to 10,000 people with blood disorders or healthy volunteers to see if they can safely join other research studies at the NIH. Participants undergo tests like blood work and imaging. If eligible, they may be offered a spot in an active study; if not, they get…

This early-stage study tests whether a new drug, ALN-F1202, is safe and tolerable in healthy adults. Researchers will monitor side effects, how the drug moves through the body, and the best dose. Participants are healthy volunteers, not patients seeking treatment.

This study uses special PET/CT scans to measure inflammation in the brains of people with Alzheimer's disease or mild cognitive impairment, compared to healthy volunteers. Nine participants will receive an experimental radioactive tracer to see how inflammation relates to Alzheim…

This study tests a tool called QbMobile that measures attention, impulsivity, and activity levels during a 10-minute test. Researchers want to see if it can provide accurate, objective data to help diagnose and treat ADHD. The study includes 700 people aged 6 to 60, both with and…

This early-stage study involves 9 healthy adults to see how the body absorbs and processes an experimental drug called ABBV-932. Researchers will measure drug levels in the blood and check if food changes absorption. The goal is to gather information, not to treat any disease.

This early-stage study is testing a new drug, JUV-161, in 72 healthy adults to see if it is safe and how the body processes it. It is the first time this drug is given to humans. The results will help plan future studies in people with muscle diseases like myotonic dystrophy.

This early-phase study tests whether a new type of PET scan can measure inflammation in the brains of people with Parkinson's disease. Eleven participants, including both Parkinson's patients and healthy volunteers, will receive an imaging drug called 18F-NOS to see if it can det…

This early-stage study looks at how healthy adult men absorb, process, and eliminate the experimental drug mosliciguat. Eight participants will receive the drug by inhalation, injection, and mouth to track its path. The goal is to understand the drug's behavior in the body, not t…

This study looks at how a drug called itraconazole changes the way ABBV-932 moves through the body. It involves 20 healthy adults who will take both medications. The goal is to check for side effects and measure drug levels in the blood. This is an early-phase study with no direc…

This study looks at how healthy adults absorb and process three different ketone supplements (monoester, tri-ester, and salt). Researchers will measure levels of a key ketone body in the blood and check for any stomach discomfort or side effects. The goal is simply to gather info…