GENETIC PREDISPOSITION

This study aims to see if a genetic test can help doctors decide which leukemia patients need a powerful antifungal drug to prevent serious mold infections during chemotherapy. About 410 adults with acute myeloid leukemia will have their DNA tested. Based on their genetic risk, t…

This study aims to understand how young adults with an inherited higher risk of cancer manage their health care after they graduate from their pediatric hospital. Researchers will follow 56 participants for up to 8 years to see if they successfully find adult doctors and continue…

This study aims to understand how parents communicate with their children and young adults about inherited genetic risks for cancer. Researchers will observe family conversations and conduct interviews to identify what helps or hinders these important discussions. The goal is to …

This study is evaluating whether genetic testing can help doctors better understand prostate cancer risk and guide treatment decisions. Researchers will analyze DNA samples from 3,000 men who have prostate cancer or are at high risk for it, looking for genetic variations linked t…

This study aims to build a collection of prostate tissue samples to better understand how prostate cancer develops in men with inherited genetic risk factors. Researchers will collect samples from men undergoing standard biopsies or prostate removal surgery, comparing those with …

This study aims to understand why some people with fatty liver disease develop liver cancer. Researchers will study 500 adults with fatty liver disease to see how specific genes and family history affect cancer risk. The goal is to create a tool to identify high-risk individuals …

This study is testing a new way to provide education about genetic cancer risk. Researchers want to see if using an AI chatbot for pre-test counseling is as effective as a video call with a human genetic counselor at getting people to complete genetic testing. They are enrolling …

This study is testing a new online platform called Nest, designed to help young adults (ages 18-39) who have had genetic testing for cancer risk. The platform provides patients and their doctors with updated information about their genetic results and recommended care plans. Rese…

This study aims to learn more about rare genetic diseases that affect the heart and blood vessels. Researchers are recruiting up to 1,000 people, including patients, their family members, and healthy volunteers, to collect medical information and samples like blood and tissue. Th…

This study aims to learn how to detect pancreatic cancer earlier by observing and collecting samples from up to 20,000 people at high risk, such as those with a strong family history or certain genetic changes. Participants will be followed over time, but this is an observational…

This study aims to understand how a person's genes and their alcohol consumption interact to increase the risk of developing liver cancer. Researchers will analyze genetic data from 1,000 people with liver disease to identify specific genetic markers. The goal is to build a bette…