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Gene-Guided antifungal strategy tested in leukemia patients

NCT ID NCT03828773

First seen Dec 10, 2025 · Last updated May 24, 2026 · Updated 19 times

Summary

This study tests whether using a person's genetic risk for mold infections can help doctors choose the right antifungal medicine for patients with acute myeloid leukemia (AML) receiving chemotherapy. About 410 adults with AML will be randomly assigned to get either standard or genetically-guided antifungal prevention. The goal is to see if the genetic approach reduces serious mold infections.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AZ Sint-Jan Hospital

    RECRUITING

    Bruges, 8000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cantonal Hospital Aarau

    RECRUITING

    Aarau, Aarau, 5001, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cantonal Hospital HFR

    RECRUITING

    Fribourg, Canton of Fribourg, 1708, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ghent University Hospital

    TERMINATED

    Ghent, Belgium, 9000, Belgium

  • Henri Mondor Hospital

    RECRUITING

    Créteil, Île-de-France Region, 94010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Basel

    RECRUITING

    Basel, Basel, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Leuven (UZ Leuven)

    RECRUITING

    Leuven, 3000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Geneva (HUG)

    RECRUITING

    Geneva, Canton of Geneva, 1211, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital of Lausanne / Centre Hospitalier Universitaire Vaudois (CHUV)

    RECRUITING

    Lausanne, Canton of Vaud, 1011, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.