GBM
Clinical trials for GBM explained in plain language.
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Experimental cocktail targets deadly brain cancer in early trial
Disease control CompletedThis early-phase study tested the safety of combining two drugs (pembrolizumab and vorinostat) with standard chemotherapy and radiation in 21 people with newly diagnosed glioblastoma, an aggressive brain cancer. The goal was to find the highest safe dose of vorinostat in this com…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 26, 2026 04:13 UTC
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Could a High-Fat diet help fight brain cancer?
Disease control CompletedThis early-phase study tested whether adding a 4-month ketogenic diet to standard radiation and chemotherapy is safe and doable for people with newly diagnosed glioblastoma, a serious brain cancer. Twenty-one adults followed personalized meal plans designed to keep their bodies i…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: Jethro Hu • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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New hope for aggressive brain cancer? drug combo tested in 29 patients
Disease control CompletedThis study tested a drug called VAL-083 combined with standard radiation for people newly diagnosed with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find a safe dose and see if the combination helps control th…
Matched conditions: GBM
Phase: PHASE2 • Sponsor: Kintara Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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Can two cancer drugs penetrate the brain? new study aims to find out
Knowledge-focused CompletedThis study looked at whether a combination of two drugs, LY3214996 and abemaciclib, can reach brain tumors in people with recurrent glioblastoma. About 42 participants took the drugs before surgery to remove their tumor. Researchers measured drug levels in the tumor tissue and sp…
Matched conditions: GBM
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Knowledge-focused
Last updated May 26, 2026 03:54 UTC