GBM

This study is testing whether a small ultrasound device implanted during surgery can temporarily open the brain's protective barrier. This opening may allow more chemotherapy drug (carboplatin) to reach recurrent glioblastoma tumors. The trial will compare this experimental appro…

This study is testing a new drug called ST101 for people with advanced solid tumors that have not responded to other treatments. The main goals are to find a safe dose and see if the drug can help control cancers like glioblastoma, melanoma, breast cancer, and prostate cancer. Th…

This early-stage study is testing a drug called niraparib for two types of aggressive brain cancer. It first checks if the drug reaches the tumor effectively after a short pre-surgery dose. If it does, participants can continue taking the drug, sometimes with radiation, to try to…

This early-stage study is testing whether adding an experimental drug called S-Gboxin to standard brain cancer treatment is safe and effective. It involves 10 adults with aggressive brain tumors like glioblastoma who have already tried standard treatments. Researchers will monito…

This early-stage study is testing whether adding a strict, high-fat ketogenic diet to standard radiation and chemotherapy is safe and feasible for adults newly diagnosed with glioblastoma, an aggressive brain cancer. For 16 weeks, participants follow personalized meal plans desig…

This study aims to see if a new type of brain scan (called DMI) can predict how well a treatment works for glioblastoma, an aggressive brain cancer. It will test the scan in patients who are also receiving an experimental drug (BPM31510) added to standard care. The main goal is t…

This study is testing whether combining a pill called niraparib with a wearable device that delivers Tumor-Treating Fields (TTFields) can help control recurrent glioblastoma, a very aggressive brain cancer. The goal is to see if the device makes the tumor cells more vulnerable to…

This early-stage trial is testing whether giving immunotherapy drugs before surgery helps the body's immune system fight recurrent glioblastoma, a fast-growing brain cancer. About 63 participants will receive either one drug, a combination of two drugs, or a placebo before their …