GBM
Clinical trials for GBM explained in plain language.
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New hope for Hard-to-Treat cancers: LP-184 enters human trials
Disease control OngoingThis early-phase study tests a new drug called LP-184 in 64 adults with advanced solid tumors (like pancreatic, lung, or breast cancer) that have stopped responding to standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors or slow their …
Matched conditions: GBM
Phase: PHASE1, PHASE2 • Sponsor: Lantern Pharma Inc. • Aim: Disease control
Last updated May 26, 2026 05:53 UTC
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New drug combo shows promise in aggressive brain cancer trial
Disease control OngoingThis early-phase trial studies whether giving two immunotherapy drugs (nivolumab and ipilimumab) before surgery can help the immune system fight recurrent glioblastoma, an aggressive brain cancer. About 63 adults whose cancer returned after standard treatment will receive the dru…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: Patrick Wen, MD • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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New drug ST101 tested in patients with advanced cancers
Disease control OngoingThis study tests a new drug called ST101 in people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to find a safe dose and see if the drug can shrink tumors. About 125 adults with cancers like glioblastoma, melanoma, breast, or prostate ca…
Matched conditions: GBM
Phase: PHASE1, PHASE2 • Sponsor: Sapience Therapeutics • Aim: Disease control
Last updated May 26, 2026 05:50 UTC
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Electric fields and drug combo shows promise for deadly brain tumor
Disease control OngoingThis study tests a combination of a drug (niraparib) and a device that delivers low-intensity electric fields (Tumor-Treating Fields) in 30 adults whose glioblastoma brain tumor has come back after standard treatment. The goal is to see if this approach can stop the tumor from gr…
Matched conditions: GBM
Phase: PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 26, 2026 05:49 UTC
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Ultrasound implant blasts open brain barrier to deliver chemo in deadly cancer trial
Disease control OngoingThis trial tests an implantable ultrasound device that temporarily opens the blood-brain barrier, allowing chemotherapy to reach brain tumors more effectively. It involves 57 patients with recurrent glioblastoma, a fast-growing brain cancer. The goal is to find a safe dose and se…
Matched conditions: GBM
Phase: PHASE1, PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated May 26, 2026 05:44 UTC
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New drug shows promise in early brain tumor trial
Disease control TerminatedThis early study tests whether adding the drug S-Gboxin to standard radiation and chemotherapy can help people with glioblastoma or diffuse midline glioma, two aggressive brain cancers. About 10 participants whose tumors have returned or worsened will receive the combination. The…
Matched conditions: GBM
Phase: PHASE1 • Sponsor: Petrov, Andrey • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New drug shows promise in hitting Hard-to-Treat brain cancers
Disease control OngoingThis study tests a drug called niraparib in people with two types of brain tumors: newly diagnosed glioblastoma and recurrent IDH-mutant glioma with ATRX loss. The goal is to see if the drug reaches the tumor and slows its growth. Up to 42 participants will receive niraparib befo…
Matched conditions: GBM
Phase: EARLY_PHASE1 • Sponsor: Nader Sanai • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New scan may predict brain tumor treatment success
Knowledge-focused TerminatedThis study looks at whether a special imaging technique called DMI can help predict how well a new drug (BPM31510) works in people with glioblastoma, a type of brain cancer. About 10 participants will receive the drug along with standard treatment and undergo imaging scans. The g…
Matched conditions: GBM
Phase: PHASE2 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 26, 2026 05:43 UTC