ESOPHAGEAL ADENOCARCINOMA

This study tested whether adding the targeted drug trastuzumab (Herceptin) to standard chemoradiation helps people with HER2-positive esophageal cancer. About 200 participants received either standard treatment or standard treatment plus trastuzumab. The main goal was to see if t…

This early study tested a new drug called Cabotamig (ARB202) in 33 adults with advanced gastrointestinal cancers (like stomach, liver, or bowel cancer) that had stopped responding to standard treatments. The drug works by targeting a marker called CDH17 on cancer cells and helpin…

This study tested a combination of three drugs—regorafenib, nivolumab, and chemotherapy—in 30 people with advanced or recurrent stomach, gastroesophageal junction, or esophageal cancer that could not be removed by surgery. The goal was to see if the combination was safe and could…

This early-stage study tested a new drug called SGN-B6A in 6 Chinese patients with advanced solid tumors (lung, head and neck, esophageal, or stomach cancers). The main goal was to check for side effects and see how the body processes the drug. It was not designed to measure if t…

This study looked at two established procedures for treating Barrett's esophagus, a condition that can lead to esophageal cancer. Researchers compared how much pain and discomfort patients felt after radiofrequency ablation versus hybrid argon plasma coagulation. The goal was to …

This study tested a procedure called spray cryotherapy, which freezes tumors inside the esophagus, to quickly improve swallowing in 15 patients with advanced esophageal cancer. Participants received the freezing treatment during a routine scope exam, before starting chemotherapy …

This study looked at over 2,000 people who had surgery to remove part of their esophagus. Researchers wanted to see if having low oxygen levels after surgery raised the chance of a leak where the esophagus was reconnected. They compared patients with low oxygen to those with norm…