ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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Could a tiny dose of radiation reboot cancer treatment?
Disease control Not yet recruitingThis study tests whether a single, low dose of radiation to all visible tumors can help immunotherapy work again in people with advanced esophageal cancer that stopped responding to standard treatment. About 32 adults will receive the radiation and continue their current immunoth…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 26, 2026 05:04 UTC
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New injection plus chemo shows promise in early trial for stomach and esophagus cancers
Disease control Not yet recruitingThis study tests whether injecting a new treatment called RP2 directly into tumors, along with standard chemotherapy (FLOT), is safe and works better than chemotherapy alone before surgery. It involves 34 adults with stage 2 or higher stomach or esophagus cancer that hasn't sprea…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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Freeze first? new trial tests liquid nitrogen before chemo for esophageal cancer
Disease control Not yet recruitingThis study tests whether freezing cancerous tissue with liquid nitrogen before chemotherapy can improve outcomes for people with advanced esophageal cancer. About 40 adults will be randomly assigned to receive either the freezing treatment plus chemo or chemo alone. The freezing …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Case Comprehensive Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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One-Time immune boost targets Hard-to-Treat stomach cancers
Disease control Not yet recruitingThis early-phase study tests whether a single dose of two immunotherapy drugs can increase cancer-fighting immune cells inside tumors. It includes 34 adults with untreated stomach or esophageal cancers that have not spread and carry a specific gene change called ARID1A. The goal …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Sponge on a string and AI could revolutionize esophageal cancer detection
Diagnosis Not yet recruitingThis study tests three new methods to diagnose Barrett's esophagus and esophageal cancer: an AI tool that predicts risk, a simple sponge-on-a-string test, and nurse navigation to help patients complete screening. About 1,010 adults at higher risk will be enrolled. The goal is to …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated May 22, 2026 13:53 UTC
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Can a $10 fungal pill stop esophageal cancer before it starts?
Prevention Not yet recruitingThis study tests whether adding the antifungal drug itraconazole to standard heat ablation therapy can prevent esophageal cancer in 64 people with high-risk Barrett's esophagus. Barrett's esophagus is a precancerous condition where the esophageal lining changes. The goal is to se…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated May 20, 2026 11:57 UTC