Diabetes mellitus, type 1
Clinical trials for Diabetes mellitus, type 1 explained in plain language.
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Experimental diabetes drug trial halted early
Disease control Stopped earlyThis study tested an experimental drug called TOL-3021 in people with type 1 diabetes to see if it could help preserve the body's ability to produce insulin. The trial enrolled 78 participants aged 12 to 41 who had been diagnosed within the last 5 years. The study was terminated …
Matched conditions: DIABETES MELLITUS, TYPE 1
Phase 2 • Sponsor: Tolerion, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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CRISPR's diabetes cell therapy trial ends early
Disease control Stopped earlyThis early-stage study tested a new treatment called VCTX211 for people with type 1 diabetes. The goal was to see if implanting these special cells could help the body make insulin and reduce the need for insulin shots. Only 5 people took part, and the study was stopped early. Th…
Matched conditions: DIABETES MELLITUS, TYPE 1
Phase 1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Promising diabetes delay study halted due to lack of participants
Disease control Stopped earlyThis study tested a low dose of a drug called ATG to see if it could delay or prevent type 1 diabetes in people at high risk. Only 2 people enrolled, so the study was stopped early. The goal was to measure how long it took for participants to develop full-blown diabetes.
Matched conditions: DIABETES MELLITUS, TYPE 1
Phase 2 • Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Can pressurized oxygen tame blood sugar spikes?
Knowledge-focused Stopped earlyThis study asks whether a single session of hyperbaric oxygen therapy (HBOT) can lower blood sugar or change glucagon levels in people with type 1 or type 2 diabetes. Participants will undergo one HBOT session and one control session (sitting in a room at normal pressure), while …
Matched conditions: DIABETES MELLITUS, TYPE 1
Sponsor: Legacy Health System • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Can two old drugs stop a dangerous diabetes complication?
Knowledge-focused Stopped earlyThis study tested whether two medications, naloxone (a nasal spray) and diazoxide (an oral pill), could prevent the body from losing its ability to sense low blood sugar—a condition called hypoglycemia unawareness. Only 4 healthy volunteers were enrolled before the trial was stop…
Matched conditions: DIABETES MELLITUS, TYPE 1
Phase 4 • Sponsor: Albert Einstein College of Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:35 UTC